Differential patterns of cross-reactive antibody response against SARS-CoV-2 spike protein detected for chronically ill and healthy COVID-19 naïve individuals

M Jaago, A Rähni, N Pupina, A Pihlak, H Sadam… - Scientific Reports, 2022 - nature.com
Immunity to previously encountered viruses can alter response to unrelated pathogens. We
reasoned that similar mechanism may also involve SARS-CoV-2 and thereby affect the …

Cross-reactive antibodies elicited to conserved epitopes on SARS-CoV-2 spike protein after infection and vaccination

ES Geanes, C LeMaster, ER Fraley, S Khanal… - Scientific Reports, 2022 - nature.com
SARS-CoV-2 is a novel betacoronavirus that caused coronavirus disease 2019 and has
resulted in millions of deaths worldwide. Novel coronavirus infections in humans have …

A comprehensive, longitudinal analysis of humoral responses specific to four recombinant antigens of SARS-CoV-2 in severe and non-severe COVID-19 patients

Y Chen, X Tong, Y Li, B Gu, J Yan, Y Liu, H Shen… - PLoS …, 2020 - journals.plos.org
There is an urgent need for effective treatment and preventive vaccine to contain this
devastating global pandemic, which requires a comprehensive understanding of humoral …

Long-term elevated inflammatory protein levels in asymptomatic SARS-CoV-2 infected individuals

L Tserel, P Jõgi, P Naaber, J Maslovskaja… - Frontiers in …, 2021 - frontiersin.org
The clinical features of SARS-CoV-2 infection range from asymptomatic to severe disease
with life-threatening complications. Understanding the persistence of immune responses in …

SARS-CoV-2 multi-antigen protein microarray for detailed characterization of antibody responses in COVID-19 patients

A Celikgil, AB Massimi, A Nakouzi, NG Herrera… - Plos one, 2023 - journals.plos.org
Antibodies against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) target
multiple epitopes on different domains of the spike protein, and other SARS-CoV-2 proteins …

SARS-CoV-2 induces a durable and antigen specific humoral immunity after asymptomatic to mild COVID-19 infection

S Havervall, A Jernbom Falk, J Klingström, H Ng… - PLoS …, 2022 - journals.plos.org
Current SARS-CoV-2 serological assays generate discrepant results, and the longitudinal
characteristics of antibodies targeting various antigens after asymptomatic to mild COVID-19 …

IgG against human betacoronavirus spike proteins correlates with SARS-CoV-2 anti-spike IgG responses and COVID-19 disease severity

J Wang, D Li, A Cameron, Q Zhou… - The Journal of …, 2022 - academic.oup.com
Background A protective antibody response to severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) is crucial to decrease morbidity and mortality from severe …

Potent anti-SARS-CoV-2 antibody responses are associated with better prognosis in hospital inpatient COVID-19 disease

PJ Tighe, RA Urbanowicz, CL Fairclough, CP McClure… - MedRxiv, 2020 - medrxiv.org
COVID-19 continues to cause a pandemic, having infected more than 20 million people
globally. Successful elimination of the SARS-CoV-2 virus will require an effective vaccine …

Longitudinal immune profiling reveals dominant epitopes mediating long-term humoral immunity in COVID-19–convalescent individuals

M Li, J Liu, R Lu, Y Zhang, M Du, M Xing, Z Wu… - Journal of Allergy and …, 2022 - Elsevier
Background Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a highly
pathogenic and contagious coronavirus that caused a global pandemic with 5.2 million …

High-resolution analysis of long-term serum antibodies in humans following convalescence of SARS-CoV-2 infection

A Facciuolo, E Scruten, S Lipsit, A Lang… - Scientific Reports, 2022 - nature.com
Long-term antibody responses to SARS-CoV-2 have focused on responses to full-length
spike protein, specific domains within spike, or nucleoprotein. In this study, we used high …