Exploring the Potential Impact of GLP-1 Receptor Agonists on Substance Use, Compulsive Behavior, and Libido: Insights from Social Media Using a Mixed-Methods …

D Arillotta, G Floresta, GD Papanti Pelletier, A Guirguis… - Brain Sciences, 2024 - mdpi.com
Glucagon-like peptide-1 (GLP-1) is involved in a range of central and peripheral pathways
related to appetitive behavior. Hence, this study explored the effects of glucagon-like peptide …

GLP-1 receptor agonists and related mental health issues; insights from a range of social media platforms using a mixed-methods approach

D Arillotta, G Floresta, A Guirguis, JM Corkery… - Brain Sciences, 2023 - mdpi.com
The emergence of glucagon-like peptide-1 receptor agonists (GLP-1 RAs; semaglutide and
others) now promises effective, non-invasive treatment of obesity for individuals with and …

Possible mechanisms underlying the effects of glucagon-like peptide-1 receptor agonist on cocaine use disorder

C Zhu, H Li, X Kong, Y Wang, T Sun… - Frontiers in …, 2022 - frontiersin.org
Cocaine use disorder (CUD) is a major public health challenge with a high relapse rate and
lack of effective pharmacotherapies; therefore, there is a substantial need to identify novel …

Can GLP-1 be a target for reward system related disorders? A qualitative synthesis and systematic review analysis of studies on palatable food, drugs of abuse, and …

CY Eren-Yazicioglu, A Yigit, RE Dogruoz… - Frontiers in Behavioral …, 2021 - frontiersin.org
The role of glucagon-like peptide 1 (GLP-1) in insulin-dependent signaling is well-known;
GLP-1 enhances glucose-dependent insulin secretion and lowers blood glucose in …

Central GLP-1 receptors: Novel molecular targets for cocaine use disorder

NS Hernandez, HD Schmidt - Physiology & behavior, 2019 - Elsevier
Given that the search for effective pharmacotherapies for cocaine use disorder has, thus far,
been fruitless, there remains a critical need for conceptually innovative approaches toward …

The central GLP-1: implications for food and drug reward

KP Skibicka - Frontiers in neuroscience, 2013 - frontiersin.org
Glucagon-like-peptide-1 (GLP-1) and its long acting analogs comprise a novel class of type
2 diabetes (T2D) treatment. What makes them unique among other T2D drugs is their …

[HTML][HTML] Glucagon-Like Peptide 1 Agonist and Effects on Reward Behaviour: A Systematic Review

S Badulescu, A Tabassum, GH Le, S Wong, L Phan… - Physiology & …, 2024 - Elsevier
Introduction The roles of metabolic signals, including Glucagon-like peptide 1 (GLP-1), have
been implicated in multiple domains outside metabolic regulation. There is a growing …

GLP-1 influences food and drug reward

MR Hayes, HD Schmidt - Current opinion in behavioral sciences, 2016 - Elsevier
Highlights•GLP-1 receptor activation will influence multiple reward-related
behaviors.•Obesity and maladaptive reward behaviors can be treated by targeting reward …

The role of glucagon‐like peptide 1 (GLP‐1) in addictive disorders

MK Klausen, M Thomsen, G Wortwein… - British Journal of …, 2022 - Wiley Online Library
Drug, alcohol and tobacco use disorders are a global burden affecting millions of people.
Despite decades of research, treatment options are sparse or missing, and relapse rates are …

The effect of glucagon-like peptide-1 (GLP-1) receptor agonists on substance use disorder (SUD)-related behavioural effects of drugs and alcohol: a systematic review

A Brunchmann, M Thomsen, A Fink-Jensen - Physiology & behavior, 2019 - Elsevier
Abstract Glucagon-like-peptide-1 (GLP-1)-receptor agonists have been proposed as
putative treatment for substance use disorders (SUD). The objective of this systematic review …