The aim of this research is to investigate the influence of different functional groups of β-
cyclodextrin (CD) in functionalizing gold nanoparticles. The functionalized nanoparticles are …

The real problem in pharmaceutical preparation is drugs' poor aqueous solubility, low
permeability through biological membranes, and short biological t1/2. Conventional drug …

We report on the therapeutic ability of a novel cyclodextrin-covered gold nanoparticle
(AuNP) carrier for noncovalent encapsulation of an anti-cancer drug. The surface of the …

Cancer, a disease of unknown origin is the second most common reason of death worldwide
after heart attacks and therefore is a major threat to human beings. Currently, chemotherapy …

Abstract Although 5-Fluorouracil (5-FU) is one of the most frequently used cytotoxic
chemotherapy drugs in the treatment of cancer, it possesses a short biological half-life and …

This study aims at tuning the properties of the nanoparticles by incorporating neodymium,
exploring the sustained release of drug, and the anticancer activity on breast cancer cells …

Recently, the improvement of the aqueous solubility, biocompatibility, and targeted delivery
effects of drug carriers became research highlights in the field of cancer therapy. A novel …

Nanotechnology has significantly impacted medicine by improving diagnostics and
therapeutics. By modifying materials at the nanoscale, we can impart unique and desirable …

Background: Paclitaxel is a potent anticancer drug that is effective against a wide spectrum
of cancers. To overcome its bioavailability problems arising from very poor aqueous …

Non-spherical structures are beneficial to advance drug delivery effectiveness compared
with common spherical ones, due to increased drug loading capability, improved bonding to …