Abstract Objective Vitamins B6 and B12 are involved in metabolic processes that decrease
neural excitation and increase inhibition. This double‐blind study investigated the effects of …

Vitamin B12 is often used to improve cognitive function, depressive symptoms, and fatigue.
In most cases, such complaints are not associated with overt vitamin B12 deficiency or …

Methods: Patients with depression and low normal B12 levels were randomized to a control
arm (antidepressant only) or treatment arm (antidepressants and injectable vitamin B12 …

Rationale A significant proportion of the general population report supplementing their diet
with one or more vitamins or minerals, with common reasons for doing so being to combat …

Background: Associations between vitamin B-12 deficiency and impaired cognitive function
and depression have been reported. Methods: A randomized placebo controlled study …

Background B vitamins have vital roles in the development, maintenance, and functioning of
the brain, while severe deficiencies have been linked to increased psychological disorders …

Objectives Despite being widely consumed, the effects of multi‐vitamin supplements on
psychological functioning have received little research attention. Methods Using a mobile …

Anxiety disorders are chronic and functionally disabling conditions with high psychological
stress, characterised by cognitive symptoms of excessive worry and focus difficulties and …

Rationale Emerging data support a role for GABA B receptors in anxiety. GABA B receptors
are comprised of a heterodimeric complex of GABA B1 and GABA B2 receptor subunits. The …

A systematic review and meta-analysis was undertaken to examine and quantify the effects
of B vitamin supplementation on mood in both healthy and 'at-risk'populations. A systematic …