Early-life adversity and physical and emotional health across the lifespan: A neuroimmune network hypothesis

R Nusslock, GE Miller - Biological psychiatry, 2016 - Elsevier
Children who experience chronic stressors are vulnerable to emotional and physical health
problems across the lifespan. This phenomenon raises questions for scientists and …

Future directions in the study of early-life stress and physical and emotional health: implications of the neuroimmune network hypothesis

CE Hostinar, R Nusslock, GE Miller - Journal of clinical child & …, 2018 - Taylor & Francis
Early-life stress is associated with increased vulnerability to physical and emotional health
problems across the lifespan. The recently developed neuroimmune network hypothesis …

Biological embedding of childhood adversity: from physiological mechanisms to clinical implications

AE Berens, SKG Jensen, CA Nelson - BMC medicine, 2017 - Springer
Background Adverse psychosocial exposures in early life, namely experiences such as child
maltreatment, caregiver stress or depression, and domestic or community violence, have …

Immune and epigenetic pathways linking childhood adversity and health across the lifespan

MA Chen, AS LeRoy, M Majd, JY Chen… - Frontiers in …, 2021 - frontiersin.org
Childhood adversity is associated with a host of mental and physical health problems across
the lifespan. Individuals who have experienced childhood adversity (eg, child abuse and …

Developmental psychoneuroendocrine and psychoneuroimmune pathways from childhood adversity to disease

KR Kuhlman, JJ Chiang, S Horn, JE Bower - … & Biobehavioral Reviews, 2017 - Elsevier
Childhood adversity has been repeatedly and robustly linked to physical and mental illness
across the lifespan. Yet, the biological pathways through which this occurs remain unclear …

Early adversity and adult health outcomes

SE Taylor, BM Way, TE Seeman - Development and …, 2011 - cambridge.org
Adversity in childhood has effects on mental and physical health, not only in childhood but
across the lifespan. A chief task of our research has been to define the pathways by which …

[HTML][HTML] Broken or maladaptive? Altered trajectories in neuroinflammation and behavior after early life adversity

P Ganguly, HC Brenhouse - Developmental cognitive neuroscience, 2015 - Elsevier
Exposure to adversity and stress early in development yields vulnerability to mental
illnesses throughout the lifespan. Growing evidence suggests that this vulnerability has …

Stressful early life experiences and immune dysregulation across the lifespan

CP Fagundes, R Glaser, JK Kiecolt-Glaser - Brain, behavior, and immunity, 2013 - Elsevier
There is considerable evidence that stressful early life events influence a variety of physical
health problems later in life. Childhood adversity has been linked to elevated rates of …

The science of early life toxic stress for pediatric practice and advocacy

SB Johnson, AW Riley, DA Granger, J Riis - Pediatrics, 2013 - publications.aap.org
Young children who experience toxic stress are at high risk for a number of health outcomes
in adulthood, including cardiovascular disease, cancers, asthma, and depression. The …

Mechanisms linking early life stress to adult health outcomes

SE Taylor - Proceedings of the National Academy of …, 2010 - National Acad Sciences
Research relating stress to health has progressed from anecdotal evidence in the 1930s
and 1940s to complex multivariate models that identify underlying longitudinal mechanisms …