Liver cirrhosis (LC) represents a significant hepatic disorder that persistently commands the
attention of the scientific community, especially concerning its pathogenesis and therapeutic …

Metabolomics is the identification and quantification of all or specified metabolites in a living
system under a specific condition or disease. Metabolomics in cirrhosis can be used in …

Chronic liver disease represents stepwise destruction of the liver parenchyma after chronic
liver injury, which is often difficult to be diagnosed accurately. Thus, the development of …

Currently there is a lack of accurate biomarkers for diagnosis and prognosis in advanced
liver diseases. Either the occurrence of first decompensation, or diagnosis of acute on …

Acute-on-chronic liver failure (ACLF) usually develops based on acute decompensation
(AD) of cirrhosis and is characterized by intense systemic inflammation, multiple organ …

Background and aim Clinical evidence for early identification and diagnosis of liver cirrhosis
(LC) caused by different types of liver disease is limited. We investigated this topic through a …

Advances in high-throughput screening of metabolic stability in liver and gut microbiota are
able to identify and quantify small-molecule metabolites (metabolome) in different cellular …

Metabolome analysis is used to evaluate the characteristics and interactions of low
molecular weight metabolites under a specific set of conditions. In cirrhosis, hepatocellular …

The application of nontargeted metabolomic profiling has recently become a powerful
noninvasive tool to discover new clinical biomarkers. This study aimed to identify metabolic …

Metabolomics is defined as the quantitative measurement of the dynamic multiparametric
metabolic response of living systems to pathophysiological stimuli or genetic modification. It …