Single-cell genomics and single-cell transcriptomics have emerged as powerful tools to
study the biology of single cells at a genome-wide scale. However, a major challenge is to …

Genome-wide analysis at the level of single cells has recently emerged as a powerful tool to
dissect genome heterogeneity in cancer, neurobiology, and development. To be truly …

Single-cell genomics is the study of the individuality of cells using omics approaches.
Although young, the field has now entered its teenage years and is beginning to show clear …

The simultaneous sequencing of a single cell's genome and transcriptome offers a powerful
means to dissect genetic variation and its effect on gene expression. Here we describe G&T …

Over the past decade, genomic analyses of single cells—the fundamental units of life—have
become possible. Single-cell DNA sequencing has shed light on biological questions that …

Recent advances in single-cell sequencing hold great potential for exploring biological
systems with unprecedented resolution. Sequencing the genome of individual cells can …

Parallel sequencing of a single cell's genome and transcriptome provides a powerful tool for
dissecting genetic variation and its relationship with gene expression. Here we present a …

Dissecting genomic diversity, one cell at a time | Nature Methods Skip to main content Thank
you for visiting nature.com. You are using a browser version with limited support for CSS. To …

Genomic studies have provided key insights into how cancers develop, evolve, metastasize
and respond to treatment. Cancers result from an interplay between mutation, selection and …

Single-cell genome sequencing has proven valuable for the detection of somatic variation,
particularly in the context of tumor evolution. Current technologies suffer from high library …