Despite therapeutic advancements, disease-free survival and overall survival of patients
with locally advanced rectal cancer have not improved in most trials as a result of distant …

While current neoadjuvant protocols have proven benefits on local control for majority of
patients with locally advanced rectal cancer, there are certain clinical conditions that require …

The treatment of locally advanced rectal cancer (LARC) has benefited from improved
surgical techniques and from the implementation of neoadjuvant chemoradiotherapy (CRT) …

The standard treatments for locally advanced rectal cancer typically involved neoadjuvant
therapy with either short-course radiation or long-course chemoradiation, followed by radical …

Despite preoperative chemoradiotherapy (CRT) and total mesorectal excision improving the
local control for locally advanced rectal cancer (LARC), oncologic outcomes and survival …

In the following review we intend to ascertain the optimal neoadjuvant therapy in patients
with locally advanced rectal cancer. In 2004, a study revealed that chemoradiotherapy …

Abstract Purpose of Review The investigation of total neoadjuvant therapy has increased
significantly in recent years, with a number of approaches being utilized in ongoing …

Aim To evaluate the feasibility and safety of total neoadjuvant therapy (TNT) in patients with
locally advanced rectal cancer (LARC) in Japan. Methods This prospective, multicenter …

Importance Treatment of locally advanced rectal (LARC) cancer involves chemoradiation,
surgery, and chemotherapy. The concept of total neoadjuvant therapy (TNT), in which …

Total neoadjuvant therapy for locally advanced rectal cancer: the fuse is lit | British Journal of
Surgery | Oxford Academic Skip to Main Content Advertisement intended for healthcare …