[HTML][HTML] CircEZH2/miR-133b/IGF2BP2 aggravates colorectal cancer progression via enhancing the stability of m6A-modified CREB1 mRNA

B Yao, Q Zhang, Z Yang, F An, H Nie, H Wang, C Yang… - Molecular cancer, 2022 - Springer
Background Aberrant expression of circular RNAs (circRNAs) contributes to the initiation
and progression of human malignancies, but the underlying mechanisms remain largely …

[HTML][HTML] CircIL4R activates the PI3K/AKT signaling pathway via the miR-761/TRIM29/PHLPP1 axis and promotes proliferation and metastasis in colorectal cancer

T Jiang, H Wang, L Liu, H Song, Y Zhang, J Wang… - Molecular cancer, 2021 - Springer
Background Accumulating studies have revealed that aberrant expression of circular RNAs
(circRNAs) is widely involved in the tumorigenesis and progression of malignant cancers …

[HTML][HTML] RNA sequencing reveals the expression profiles of circRNA and indicates that circDDX17 acts as a tumor suppressor in colorectal cancer

XN Li, ZJ Wang, CX Ye, BC Zhao, ZL Li… - Journal of Experimental & …, 2018 - Springer
Abstract Background Circular RNA (circRNA) is a novel class of noncoding RNAs with
functions in various pathophysiological activities. However, the expression profiles and …

Hsa_circRNA_002144 promotes growth and metastasis of colorectal cancer through regulating miR-615-5p/LARP1/mTOR pathway

M Wu, C Kong, M Cai, W Huang, Y Chen… - …, 2021 - academic.oup.com
CircRNAs (circular RNAs), recently identified as a critical regulator in tumorigenesis,
participate in CRC (colorectal cancer) growth. However, the role of hsa_circRNA_002144 in …

[HTML][HTML] Emerging roles of circRNA_001569 targeting miR-145 in the proliferation and invasion of colorectal cancer

H Xie, X Ren, S Xin, X Lan, G Lu, Y Lin, S Yang… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Circular RNAs (circRNAs), a large class of RNAs, have recently shown huge capabilities as
gene regulators in mammals. Some of them bind with microRNAs (miRNAs) and act as …

Comprehensive profile of differentially expressed circular RNAs reveals that hsa_circ_0000069 is upregulated and promotes cell proliferation, migration, and invasion …

J Guo, W Feng, J Shao, L Wan, M Huang… - OncoTargets and …, 2016 - Taylor & Francis
Background Nowadays, despite great progress in cancer research, the detailed
mechanisms of colorectal cancer (CRC) are still poorly understood. Circular RNAs …

[HTML][HTML] Circular RNA circHERC4 as a novel oncogenic driver to promote tumor metastasis via the miR-556-5p/CTBP2/E-cadherin axis in colorectal cancer

J He, Z Chu, W Lai, Q Lan, Y Zeng, D Lu, S Jin… - Journal of hematology & …, 2021 - Springer
Background The main cause of death in colorectal cancer patients is metastasis.
Accumulating evidences suggest that circRNA plays pivotal roles in cancer initiation and …

Hsa_circ_101555 functions as a competing endogenous RNA of miR-597-5p to promote colorectal cancer progression

Z Chen, R Ren, D Wan, Y Wang, X Xue, M Jiang… - Oncogene, 2019 - nature.com
CircRNAs have been reported to exert momentous roles in regulating pathophysiological
process and guiding clinical diagnosis and treatment in colorectal cancer (CRC). However …

[HTML][HTML] Two circPPFIA1s negatively regulate liver metastasis of colon cancer via miR-155-5p/CDX1 and HuR/RAB36

H Ji, TW Kim, WJ Lee, SD Jeong, YB Cho, HH Kim - Molecular Cancer, 2022 - Springer
Abstract Background Circular RNAs (circRNAs) play a critical role in colorectal cancer
(CRC) progression, including metastasis. However, the detailed molecular mechanism is not …

CircRNA_100290 promotes colorectal cancer progression through miR-516b-induced downregulation of FZD4 expression and Wnt/β-catenin signaling

G Fang, BL Ye, BR Hu, XJ Ruan, YX Shi - Biochemical and biophysical …, 2018 - Elsevier
Accumulating evidence indicates that circular RNAs (circRNA) exert crucial functions in the
development and advance of cancers. CircRNA_100290 has been reported to promote …