[HTML][HTML] Effects of potent neutralizing antibodies from convalescent plasma in patients hospitalized for severe SARS-CoV-2 infection

A Gharbharan, CCE Jordans… - Nature …, 2021 - nature.com
In a randomized clinical trial of 86 hospitalized COVID-19 patients comparing standard care
to treatment with 300mL convalescent plasma containing high titers of neutralizing SARS …

Convalescent plasma for COVID-19. A randomized clinical trial

A Gharbharan, CCE Jordans, C Geurtsvankessel… - MEDRxiv, 2020 - medrxiv.org
Structured abstract for full paper Background After recovery from COVID-19, most patients
have anti-SARS-CoV-2 neutralizing antibodies. Their convalescent plasma could be an …

[HTML][HTML] Antibodies from convalescent plasma promote SARS-CoV-2 clearance in individuals with and without endogenous antibody response

M Marconato, IA Abela, A Hauser… - The Journal of …, 2022 - Am Soc Clin Investig
BACKGROUND Neutralizing antibodies are considered a key correlate of protection by
current SARS-CoV-2 vaccines. The manner in which human infections respond to …

Current studies of convalescent plasma therapy for COVID-19 may underestimate risk of antibody-dependent enhancement

AB Fleming, V Raabe - Journal of Clinical Virology, 2020 - ncbi.nlm.nih.gov
As more and more patients recover from coronavirus disease 2019 (COVID-19) in the
coming weeks, convalescent plasma will become increasingly accessible as a treatment …

[HTML][HTML] Convalescent plasma treatment of severe COVID-19: a propensity score–matched control study

STH Liu, HM Lin, I Baine, A Wajnberg, JP Gumprecht… - Nature medicine, 2020 - nature.com
Abstract Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2), is a new human disease with few effective …

[HTML][HTML] A randomized double-blind controlled trial of convalescent plasma in adults with severe COVID-19

MR O'Donnell, B Grinsztejn… - The Journal of …, 2021 - Am Soc Clin Investig
BACKGROUND Although convalescent plasma has been widely used to treat severe
coronavirus disease 2019 (COVID-19), data from randomized controlled trials that support …

[HTML][HTML] Convalescent plasma antibody levels and the risk of death from Covid-19

MJ Joyner, RE Carter, JW Senefeld… - … England Journal of …, 2021 - Mass Medical Soc
Background Convalescent plasma has been widely used to treat coronavirus disease 2019
(Covid-19) under the presumption that such plasma contains potentially therapeutic …

Convalescent plasma in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial

RECOVERY Collaborative Group, PW Horby… - MedRxiv, 2021 - medrxiv.org
Background Treatment of COVID-19 patients with plasma containing anti-SARS-CoV-2
antibodies may have a beneficial effect on clinical outcomes. We aimed to evaluate the …

[HTML][HTML] Factors associated with good patient outcomes following convalescent plasma in COVID-19: a prospective phase II clinical trial

D Ibrahim, L Dulipsingh, L Zapatka, R Eadie… - Infectious diseases and …, 2020 - Springer
Abstract Introduction Coronavirus disease 2019 (COVID-19) is a viral respiratory syndrome
caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). This novel virus …

[HTML][HTML] Convalescent plasma for hospitalized patients with COVID-19: an open-label, randomized controlled trial

P Bégin, J Callum, E Jamula, R Cook, NM Heddle… - Nature medicine, 2021 - nature.com
The efficacy of convalescent plasma for coronavirus disease 2019 (COVID-19) is unclear.
Although most randomized controlled trials have shown negative results, uncontrolled …