Formation of flavorant–propylene glycol adducts with novel toxicological properties in chemically unstable e-cigarette liquids

HC Erythropel, SV Jabba, TM DeWinter… - Nicotine and …, 2019 - academic.oup.com
Introduction “Vaping” electronic cigarettes (e-cigarettes) is increasingly popular with youth,
driven by the wide range of available flavors, often created using flavor aldehydes. The …

Chemical adducts of reactive flavor aldehydes formed in e-cigarette liquids are cytotoxic and inhibit mitochondrial function in respiratory epithelial cells

SV Jabba, AN Diaz, HC Erythropel… - Nicotine and …, 2020 - academic.oup.com
Introduction Flavor aldehydes in e-cigarettes, including vanillin, ethyl vanillin (vanilla), and
benzaldehyde (berry/fruit), rapidly undergo chemical reactions with the e-liquid solvents …

Flavoring compounds dominate toxic aldehyde production during e-cigarette vaping

A Khlystov, V Samburova - Environmental science & technology, 2016 - ACS Publications
The growing popularity of electronic cigarettes (e-cigarettes) raises concerns about the
possibility of adverse health effects to primary users and people exposed to e-cigarette …

[HTML][HTML] Characterization of potential impurities and degradation products in electronic cigarette formulations and aerosols

JW Flora, N Meruva, CB Huang, CT Wilkinson… - Regulatory Toxicology …, 2016 - Elsevier
E-cigarettes are gaining popularity in the US as well as in other global markets. Currently,
limited published analytical data characterizing e-cigarette formulations (e-liquids) and …

Influence of the e-cigarette emission profile by the ratio of glycerol to propylene glycol in e-liquid composition

BG Ooi, D Dutta, K Kazipeta, NS Chong - ACS omega, 2019 - ACS Publications
The use of electronic cigarettes (E-cig) is popular because of the perception that they are
less addictive and safer compared to the traditional cigarettes. Nevertheless, there are still …

Solvent chemistry in the electronic cigarette reaction vessel

RP Jensen, RM Strongin, DH Peyton - Scientific reports, 2017 - nature.com
Abstract Knowledge of the mechanism of formation, levels and toxicological profiles of the
chemical products in the aerosols (ie, vapor plus particulate phases) of e-cigarettes is …

Chemical hazards present in liquids and vapors of electronic cigarettes

C Hutzler, M Paschke, S Kruschinski, F Henkler… - Archives of …, 2014 - Springer
Electronic (e-) cigarettes have emerged in recent years as putative alternative to
conventional tobacco cigarettes. These products do not contain typical carcinogens that are …

Electronic cigarette-generated aldehydes: the contribution of e-liquid components to their formation and the use of urinary aldehyde metabolites as biomarkers of …

DJ Conklin, MA Ogunwale, Y Chen… - Aerosol Science and …, 2018 - Taylor & Francis
Electronic cigarettes (e-cigarette) have emerged as a popular electronic nicotine delivery
system (ENDS) in the last decade. Despite the absence of combustion products and toxins …

Analytical and toxicological evaluation of flavor chemicals in electronic cigarette refill fluids

RZ Behar, W Luo, KJ McWhirter, JF Pankow… - Scientific reports, 2018 - nature.com
Thousands of electronic cigarette refill fluids are commercially available. The concentrations
of nicotine and the solvents, but not the flavor chemicals, are often disclosed on product …

Flavour chemicals in electronic cigarette fluids

PA Tierney, CD Karpinski, JE Brown, W Luo… - Tobacco …, 2016 - tobaccocontrol.bmj.com
Background Most e-cigarette liquids contain flavour chemicals. Flavour chemicals certified
as safe for ingestion by the Flavor Extracts Manufacturers Association may not be safe for …