Morphological, cellular, and molecular basis of brain infection in COVID-19 patients

F Crunfli, VC Carregari, FP Veras… - Proceedings of the …, 2022 - National Acad Sciences
Although increasing evidence confirms neuropsychiatric manifestations associated mainly
with severe COVID-19 infection, long-term neuropsychiatric dysfunction (recently …

[HTML][HTML] SARS-CoV-2 infects brain astrocytes of COVID-19 patients and impairs neuronal viability

F Crunfli, VC Carregari, FP Veras, PH Vendramini… - MedRxiv, 2021 - medrxiv.org
One increasingly documented tendency of COVID-19 patients is to exhibit neuropsychiatric
and neurological symptoms. Here we found that anxiety and cognitive impairment are …

In SARS-CoV-2, astrocytes are in it for the long haul

S Huang, G Fishell - … of the National Academy of Sciences, 2022 - National Acad Sciences
The most dire consequences of severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2) infection may not manifest during the initial infection but appear later and are …

The neurobiology of SARS-CoV-2 infection

J Meinhardt, S Streit, C Dittmayer, RV Manitius… - Nature Reviews …, 2024 - nature.com
Worldwide, over 694 million people have been infected with SARS-CoV-2, with an estimated
55–60% of those infected developing COVID-19. Since the beginning of the pandemic in …

[HTML][HTML] Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and glial cells: Insights and perspectives

G Vargas, LHM Geraldo, NG Salomão, MV Paes… - Brain, behavior, & …, 2020 - Elsevier
In December 2019, a pneumonia outbreak was reported in Wuhan, Hubei province, China.
Since then, the World Health Organization declared a public health emergency of …

SARS-CoV-2 invades cognitive centers of the brain and induces Alzheimer's-like neuropathology

WB Shen, M Elahi, J Logue, P Yang, L Baracco… - BioRxiv, 2022 - biorxiv.org
The neurotropism of SARS-CoV-2 and the phenotypes of infected neurons are still in
debate. Long COVID manifests with “brain diseases” and the cause of these brain …

Proteomic and transcriptomic profiling of brainstem, cerebellum and olfactory tissues in early-and late-phase COVID-19

J Radke, J Meinhardt, T Aschman, RL Chua… - Nature …, 2024 - nature.com
Neurological symptoms, including cognitive impairment and fatigue, can occur in both the
acute infection phase of coronavirus disease 2019 (COVID-19) and at later stages, yet the …

Neuropathology and virus in brain of SARS-CoV-2 infected non-human primates

I Rutkai, MG Mayer, LM Hellmers, B Ning… - Nature …, 2022 - nature.com
Neurological manifestations are a significant complication of coronavirus disease (COVID-
19), but underlying mechanisms aren't well understood. The development of animal models …

COVID-19 induces CNS cytokine expression and loss of hippocampal neurogenesis

AL Soung, A Vanderheiden, AS Nordvig, CA Sissoko… - Brain, 2022 - academic.oup.com
Infection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is
associated with acute and postacute cognitive and neuropsychiatric symptoms including …

What can we learn from brain autopsies in COVID-19?

SS Mukerji, IH Solomon - Neuroscience letters, 2021 - Elsevier
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of
coronavirus disease 2019 (COVID-19) for which there have been over 50 million confirmed …