Association between the expression of toll-like receptors, cytokines, and homeostatic chemokines in SARS-CoV-2 infection and COVID-19 severity

W Alturaiki, H Alkadi, S Alamri, ME Awadalla, A Alfaez… - Heliyon, 2023 - cell.com
The recent identification of the involvement of the immune system response in the severity
and mortality of acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection highlights …

Higher expression of monocyte chemotactic protein 1 in mild COVID-19 patients might be correlated with inhibition of Type I IFN signaling

X Xi, Y Guo, M Zhu, Y Wei, G Li, B Du, Y Wang - Virology journal, 2021 - Springer
Background Chemokine levels in severe coronavirus disease 2019 (COVID-19) patients
have been shown to be markedly elevated. But the role of chemokines in mild COVID-19 …

Serum inflammatory factors are positively correlated with the production of specific antibodies in coronavirus disease 2019 patients

M Zheng, Y Gao, S Liu, D Sun, F Yang, L Zong… - Cellular & Molecular …, 2020 - nature.com
The ongoing spread of coronavirus disease 2019 (COVID-19) constitutes an international
concern on an unprecedented scale. To date, over 23 million people have been diagnosed …

[HTML][HTML] Increased LPS levels coexist with systemic inflammation and result in monocyte activation in severe COVID-19 patients

PC Teixeira, GP Dorneles, PC Santana Filho… - International …, 2021 - Elsevier
Mucosal barrier alterations may play a role in the pathogenesis of several diseases,
including COVID-19. In this study we evaluate the association between bacterial …

CXCL8, CCL2, and CMV seropositivity as new prognostic factors for a severe COVID-19 course

E Pius-Sadowska, A Niedźwiedź, P Kulig… - International journal of …, 2022 - mdpi.com
The exact pathophysiology of severe COVID-19 is not entirely elucidated, but it has been
established that hyperinflammatory responses and cytokine storms play important roles. The …

Multi-cohort study on cytokine and chemokine profiles in the progression of COVID-19

C Huang, X Hu, D Wang, R Gong, Q Wang, F Ren… - Scientific Reports, 2024 - nature.com
Various substances in the blood plasma serve as prognostic indicators of the progression of
COVID-19. Consequently, multi-omics studies, such as proteomic and metabolomics, are …

Cytokine storm may not be the chief culprit for the deterioration of COVID-19

Y Gao, C Wang, K Kang, Y Peng, Y Luo, H Liu… - Viral …, 2021 - liebertpub.com
COVID-19 is spreading and ravaging all over the world, and the number of deaths is
increasing day by day without downward trend. However, there is limited knowledge of …

The pro-inflammatory chemokines CXCL9, CXCL10 and CXCL11 are upregulated following SARS-CoV-2 infection in an AKT-dependent manner

V Callahan, S Hawks, MA Crawford, CW Lehman… - Viruses, 2021 - mdpi.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a highly transmissible
RNA virus that is the causative agent of the Coronavirus disease 2019 (COVID-19) …

Pro-inflammatory CXCL-10, TNF-α, IL-1β, and IL-6: biomarkers of SARS-CoV-2 infection

AS Tripathy, S Vishwakarma, D Trimbake, YK Gurav… - Archives of …, 2021 - Springer
Currently, the world is witnessing the pandemic of COVID-19, a disease caused by the novel
coronavirus SARS-CoV-2. Reported differences in clinical manifestations and outcomes in …

Pro-and anti-inflammatory responses in severe COVID-19-induced acute respiratory distress syndrome—an observational pilot study

Q Notz, M Schmalzing, F Wedekink… - Frontiers in …, 2020 - frontiersin.org
Objectives The severity of Coronavirus Disease 2019 (COVID-19) is largely determined by
the immune response. First studies indicate altered lymphocyte counts and function …