Targeted suppression of miRNA-33 using pHLIP improves atherosclerosis regression

X Zhang, N Rotllan, A Canfrán-Duque, J Sun… - Circulation …, 2022 - Am Heart Assoc
Background: miRNA therapeutics have gained attention during the past decade. These
oligonucleotide treatments can modulate the expression of miRNAs in vivo and could be …

Therapeutic Silencing of MicroRNA-33 Inhibits the Progression of Atherosclerosis in Ldlr−/− Mice—Brief Report

N Rotllan, CM Ramírez, B Aryal, CC Esau… - … , and vascular biology, 2013 - Am Heart Assoc
Objective—To study the efficacy of anti–miRNA-33 therapy on the progression of
atherosclerosis. Approach and Results—Ldlr−/− mice were injected subcutaneously with …

[HTML][HTML] Functions of microRNA-33a/b and microRNA therapeutics

K Ono - Journal of cardiology, 2016 - Elsevier
Atherosclerosis is a chronic inflammatory disease of the arterial wall. It is characterized by
subendothelial accumulation of low-density lipoprotein cholesterol, and its subsequent …

[Retraction] MicroRNA-134 Promotes the Development of Atherosclerosis Via the ANGPTL4/LPL Pathway in Apolipoprotein E Knockout Mice

Q Ye, GP Tian, HP Cheng, X Zhang, X Ou… - … of Atherosclerosis and …, 2018 - jstage.jst.go.jp
Aims: Atherosclerosis is the most common cause of cardiovascular disease, such as
myocardial infarc-tion and stroke. Previous study revealed that microRNA (miR)-134 …

MiR-377-3p inhibits atherosclerosis-associated vascular smooth muscle cell proliferation and migration via targeting neuropilin2

H Wang, Z Wei, H Li, Y Guan, Z Han… - Bioscience …, 2020 - portlandpress.com
Vascular smooth muscle cell (VSMC) proliferation and migration are vital to atherosclerosis
(AS) development and plaque rupture. MicroRNA-377-3p (miR-377-3p) has been reported …

MicroRNAs and lipoproteins: a connection beyond atherosclerosis?

GD Norata, F Sala, AL Catapano… - Atherosclerosis, 2013 - Elsevier
MicroRNAs (miRNAs) are short non-coding RNAs involved in the regulation of gene
expression at the post-transcriptional level that have been involved in the pathogenesis of a …

Induction of MiR133a expression by IL-19 targets LDLRAP1 and reduces oxLDL uptake in VSMC

K Gabunia, AB Herman, M Ray, SE Kelemen… - Journal of molecular and …, 2017 - Elsevier
The transformation of vascular smooth muscle cells [VSMC] into foam cells leading to
increased plaque size and decreased stability is a key, yet understudied step in …

microRNAs in lipoprotein metabolism and cardiometabolic disorders

N Rotllan, N Price, P Pati, L Goedeke… - Atherosclerosis, 2016 - Elsevier
Circulating levels of low-density lipoprotein cholesterol (LDL), and high-density lipoprotein
cholesterol (HDL) are two of the most important risk factors for the development of …

MicroRNA‐33 Deficiency Reduces the Progression of Atherosclerotic Plaque in ApoE−/− Mice

T Horie, O Baba, Y Kuwabara, Y Chujo… - Journal of the …, 2012 - Am Heart Assoc
Background Cholesterol efflux from cells to apolipoprotein A‐I (apoA‐I) acceptors via the
ATP‐binding cassette transporters ABCA 1 and ABCG 1 is thought to be central in the …

MicroRNAs in atherosclerosis and lipoprotein metabolism

KC Vickers, AT Remaley - Current Opinion in Endocrinology …, 2010 - journals.lww.com
MicroRNAs in atherosclerosis and lipoprotein metabolism : Current Opinion in
Endocrinology, Diabetes and Obesity MicroRNAs in atherosclerosis and lipoprotein …