MicroRNA: dynamic regulators of macrophage polarization and plasticity

JB Self-Fordham, AR Naqvi, JR Uttamani… - Frontiers in …, 2017 - frontiersin.org
The ability of a healthy immune system to clear the plethora of antigens it encounters
incessantly relies on the enormous plasticity displayed by the comprising cell types …

Transcriptional regulation of macrophages polarization by MicroRNAs

H Li, T Jiang, MQ Li, XL Zheng, GJ Zhao - Frontiers in immunology, 2018 - frontiersin.org
Diversity and plasticity are the hallmarks of cells from the monocyte–macrophage lineage.
Macrophages undergo classical M1 or alternative M2 activation in response to the …

Next-generation sequencing of microRNAs uncovers expression signatures in polarized macrophages

V Cobos Jiménez, EJ Bradley… - Physiological …, 2014 - journals.physiology.org
microRNAs (miRNAs) are small noncoding RNAs that regulate gene expression at a
posttranscriptional level and play a crucial role in the development of cells of the immune …

Emerging role of micro RNA s in regulating macrophage activation and polarization in immune response and inflammation

X Wu, Y Dai, Y Yang, C Huang, X Meng, B Wu… - Immunology, 2016 - Wiley Online Library
Diversity and plasticity are hallmarks of macrophages. Classically activated macrophages
are considered to promote T helper type 1 responses and have strong microbicidal, pro …

MicroRNAs in immune response and macrophage polarization

G Liu, E Abraham - Arteriosclerosis, thrombosis, and vascular …, 2013 - Am Heart Assoc
Inflammation is essential to combat invading microbial pathogens. In this process, the
involvement of multiple immune cell populations is crucial in mounting an optimum immune …

MicroRNAs and the resolution phase of inflammation in macrophages

MM Alam, LA O'Neill - European journal of immunology, 2011 - Wiley Online Library
Toll‐like receptors (TLRs) signal the presence of pathogens and tissue injury, triggering the
inflammatory process in macrophages. The goal of inflammation is to resolve the injury and …

miRNA in macrophage development and function

S Roy - Antioxidants & Redox Signaling, 2016 - liebertpub.com
Significance: MicroRNAs (miRNAs) control cellular gene expression via primarily binding to
3′ or 5′ untranslated region of the target transcript leading to translational repression or …

Time Series miRNA-mRNA integrated analysis reveals critical miRNAs and targets in macrophage polarization

L Lu, S McCurdy, S Huang, X Zhu, K Peplowska… - Scientific reports, 2016 - nature.com
Polarization of macrophages is regulated through complex signaling networks. Correlating
miRNA and mRNA expression over time after macrophage polarization has not yet been …

MicroRNAs: fine tuners of monocyte heterogeneity

I Duroux-Richard, M Robin, C Peillex… - Frontiers in …, 2019 - frontiersin.org
Small non-coding microRNAs (miRNAs) have been found to play critical roles in many
biological processes by controlling gene expression at the post-transcriptional level. They …

The multifaceted interface between cytokines and microRNAs: an ancient mechanism to regulate the good and the bad of inflammation

S Garavelli, V De Rosa, P De Candia - Frontiers in immunology, 2018 - frontiersin.org
MicroRNAs (miRNAs) are evolutionary conserved small non-coding RNA molecules that
affect gene expression by binding to target messenger RNAs and play a role in biological …