Some transcription factors contain stretches of polyglutamine encoded by repeats of the
trinucleotide CAG. Expansion of the CAG repeat in the androgen receptor (AR) has been …

We have reported that polyglutamine (polyGln)-expanded human androgen receptors (hAR)
have reduced transactivational competence in transfected cells. We presumed that maximal …

The molecular basis for partial androgen insensitivity associated with adult onset
spinal/bulbar muscular atrophy was investigated by transient transfection of human …

X-linked spinal and bulbar muscular atrophy (SBMA) is a rare form of motor neuron
degeneration linked to a CAG repeat expansion in the first exon of the androgen receptor …

The androgen testosterone and its metabolite dihydrotestosterone exert their effects on gene
expression and thus effect maleness via the androgen receptor (AR). A diverse range of …

The androgen receptor (AR) is a ligand-activated transcription factor which is responsible for
the androgen responsiveness of target cells. Several types of mutations have been found in …

Expansion of the long (CAG; glutamine) n repeat in the first exon of the X–linked human
androgen receptor gene (hAR) causes spinal and bulbar muscular atrophy, frequently in …

Spinal and bulbar muscular atrophy (SBMA) is an inherited form of lower motor neuron
degeneration caused by expansion of a CAG repeat in the androgen receptor (AR) gene. To …

The X-linked androgen receptor (AR) gene contains two polymorphic trinucleotide repeat
segments that code for polyglutamine and polyglycine tracts in the N-terminal trans …

X-linked spinal and bulbar muscular atrophy (SBMA) is caused by a CAG repeat expansion
in the first exon of the androgen receptor (AR) gene. Disease-associated alleles (37–66 …