Choice of Voxel-based Morphometry processing pipeline drives variability in the location of neuroanatomical brain markers

X Zhou, R Wu, Y Zeng, Z Qi, S Ferraro, L Xu… - Communications …, 2022 - nature.com
Fundamental and clinical neuroscience has benefited tremendously from the development
of automated computational analyses. In excess of 600 human neuroimaging papers using …

Statistical parametric mapping of brain morphology: sensitivity is dramatically increased by using brain-extracted images as inputs

G Fein, B Landman, H Tran, J Barakos, K Moon… - Neuroimage, 2006 - Elsevier
A major attraction of voxel-based morphometry (VBM) is that it allows researchers to explore
large datasets with minimal human intervention. However, the validity and sensitivity of the …

Multi-site voxel-based morphometry—not quite there yet

NK Focke, G Helms, S Kaspar, C Diederich, V Tóth… - Neuroimage, 2011 - Elsevier
Voxel-based morphometry (VBM) is a widely applied method in computational
neurosciences but it is currently recommended to compare only data collected at a single …

Evaluation of voxel-based morphometry for focal lesion detection in individuals

S Mehta, TJ Grabowski, Y Trivedi, H Damasio - Neuroimage, 2003 - Elsevier
Voxel-based morphometry (VBM) is an automated statistical technique used to detect
regional differences in tissue density and tissue amount based on spatially standardized …

Why voxel-based morphometric analysis should be used with great caution when characterizing group differences

C Davatzikos - Neuroimage, 2004 - Elsevier
A variety of voxel-based morphometric analysis methods have been adopted by the
neuroimaging community in the recent years. In this commentary we describe why voxel …

Comparison of different methodological implementations of voxel-based morphometry in neurodegenerative disease

ML Senjem, JL Gunter, MM Shiung, RC Petersen… - Neuroimage, 2005 - Elsevier
Voxel-based morphometry (VBM) is a popular method for probing inter-group differences in
brain morphology. Variation in the detailed implementation of the algorithm, however, will …

Age-related differences in regional brain volumes: a comparison of optimized voxel-based morphometry to manual volumetry

KM Kennedy, KI Erickson, KM Rodrigue, MW Voss… - Neurobiology of …, 2009 - Elsevier
Regional manual volumetry is the gold standard of in vivo neuroanatomy, but is labor-
intensive, can be imperfectly reliable, and allows for measuring limited number of regions …

[HTML][HTML] False positive rates in Voxel-based Morphometry studies of the human brain: should we be worried?

C Scarpazza, S Tognin, S Frisciata, G Sartori… - Neuroscience & …, 2015 - Elsevier
Voxel-based Morphometry (VBM) is a widely used automated technique for the analysis of
neuroanatomical images. Despite its popularity within the neuroimaging community, there …

Voxel-based morphometry: an automated technique for assessing structural changes in the brain

JL Whitwell - Journal of Neuroscience, 2009 - Soc Neuroscience
The identification of structural changes in the brain on magnetic resonance imaging (MRI)
scans is increasingly important in the study of neurological and psychiatric diseases. MRI …

When the single matters more than the group: very high false positive rates in single case Voxel Based Morphometry

C Scarpazza, G Sartori, MS De Simone, A Mechelli - Neuroimage, 2013 - Elsevier
Voxel Based Morphometry (VBM) studies typically involve a comparison between groups of
individuals; this approach however does not allow inferences to be made at the level of the …