Vitamin K–sources, physiological role, kinetics, deficiency, detection, therapeutic use, and toxicity

P Mladěnka, K Macáková, L Kujovská Krčmová… - Nutrition …, 2022 - academic.oup.com
Vitamin K is traditionally connected with blood coagulation, since it is needed for the
posttranslational modification of 7 proteins involved in this cascade. However, it is also …

Relationship between structure and biological activity of various vitamin K forms

K Bus, A Szterk - Foods, 2021 - mdpi.com
Vitamin K is involved many biological processes, such as the regulation of blood
coagulation, prevention of vascular calcification, bone metabolism and modulation of cell …

Vitamin K: double bonds beyond coagulation insights into differences between vitamin K1 and K2 in health and disease

M Halder, P Petsophonsakul, AC Akbulut… - International journal of …, 2019 - mdpi.com
Vitamin K is an essential bioactive compound required for optimal body function. Vitamin K
can be present in various isoforms, distinguishable by two main structures, namely …

Vitamin K and osteoporosis: myth or reality?

A Palermo, D Tuccinardi, L D'Onofrio, M Watanabe… - Metabolism, 2017 - Elsevier
Vitamin K is a liposoluble vitamin. The predominant dietary form, phylloquinone or vitamin
K1, is found in plants and green vegetables; whereas menaquinone, or vitamin K2, is …

Chemistry, nutritional sources, tissue distribution and metabolism of vitamin K with special reference to bone health

MJ Shearer, A Bach, M Kohlmeier - The Journal of nutrition, 1996 - Elsevier
Vitamin K occurs in anture as a series of compounds with a common 2-methyl-1, 4
naphthoquinone nucleus and differing isoprenoid side chains at the 3 position. They …

Beyond deficiency: potential benefits of increased intakes of vitamin K for bone and vascular health

C Vermeer, MJ Shearer, A Zittermann… - European journal of …, 2004 - Springer
Vitamin K is well known for its role in the synthesis of a number of blood coagulation factors.
During recent years vitamin K-dependent proteins were discovered to be of vital importance …

Vitamins K1 and K2: the emerging group of vitamins required for human health

GK Schwalfenberg - Journal of nutrition and metabolism, 2017 - Wiley Online Library
Objective. To review the evidence for the use of vitamin K supplementation in clinical
conditions such as osteoporosis, vascular calcification, arthritis, cancer, renal calculi …

The discovery of vitamin K and its clinical applications

G Ferland - Annals of Nutrition and Metabolism, 2012 - karger.com
Vitamin K was discovered fortuitously in 1929 as part of experiments on sterol metabolism
and was immediately associated with blood coagulation. In the decade that followed, the …

Vitamin K2 needs an RDI separate from vitamin K1

AC Akbulut, A Pavlic, P Petsophonsakul, M Halder… - Nutrients, 2020 - mdpi.com
Vitamin K and its essential role in coagulation (vitamin K [Koagulation]) have been well
established and accepted the world over. Many countries have a Recommended Daily …

Vitamin K: an old vitamin in a new perspective

U Gröber, J Reichrath, MF Holick… - Dermato-endocrinology, 2014 - Taylor & Francis
The topic of “Vitamin K” is currently booming on the health products market. Vitamin K is
known to be important for blood coagulation. Current research increasingly indicates that the …