[HTML][HTML] Integrative analysis of clinical health records, imaging and pathogen genomics identifies personalized predictors of disease prognosis in tuberculosis

A Sambarey, K Smith, C Chung, HS Arora, Z Yang… - medRxiv, 2022 - ncbi.nlm.nih.gov
Tuberculosis (TB) afflicts over 10 million people every year and its global burden is
projected to increase dramatically due to multidrug-resistant TB (MDR-TB). The Covid-19 …

Analysis of a Large Patient-Level Dataset to Predict Outcome of Treatment for Drug-Resistant Tuberculosis

Q Wang, J Gu, A Gabrielian, G Rosenfeld, M Quiñones… - medRxiv, 2022 - medrxiv.org
ABSTRACT BACKGROUND Drug-resistant (DR) tuberculosis treatment is challenging and
frequently leads to poor outcomes. An international collaboration, the National Institute of …

[HTML][HTML] Integrative analysis of multimodal patient data identifies personalized predictors of tuberculosis treatment prognosis

A Sambarey, K Smith, C Chung, HS Arora, Z Yang… - Iscience, 2024 - cell.com
Summary Tuberculosis (TB) afflicted 10.6 million people in 2021, and its global burden is
increasing due to multidrug-resistant TB (MDR-TB) and extensively resistant TB (XDR-TB) …

Integrative Analysis of Multimodal Patient Data Identifies Efficacious Drug Regimens and Personalized Predictors of Tuberculosis Treatment Prognosis

A Sambarey, K Smith, C Chung, HS Arora… - Available at SSRN … - papers.ssrn.com
Abstract Tuberculosis (TB) afflicted 10.6 million people in 2021, and its global burden is
increasing due to multidrug-resistant TB (MDR-TB) and extensively resistant TB (XDR-TB) …

Unravelling the transcriptome of the human tuberculosis lesion and its clinical implications

A Despuig, KL Fonseca, D Habgood-Coote… - medRxiv, 2022 - medrxiv.org
The granuloma is a complex structure, contributing to the overall spectrum of tuberculosis
(TB). We characterised 44 fresh human pulmonary TB lesion samples from 13 patients (drug …

Multi-cohort analysis reveals immune subtypes and predictive biomarkers in tuberculosis

L Li, T Wang, Z Chen, J Liang, H Ding - Scientific Reports, 2024 - nature.com
Tuberculosis (TB) remains a significant global health threat, necessitating effective
strategies for diagnosis, prognosis, and treatment. This study employs a multi-cohort …

[PDF][PDF] Biomarkers to predict Tuberculosis treatment

I Boshielo - 2023 - wiredspace.wits.ac.za
Tuberculosis (TB) caused by Mycobacterium tuberculosis (Mtb) is a disease killing millions
of people globally (Lourens et al., 2019). TB infection is established when an individual …

Automatic discovery of clinically interpretable imaging biomarkers for Mycobacterium tuberculosis supersusceptibility using deep learning

TE Tavolara, MKK Niazi, M Ginese, C Piedra-Mora… - …, 2020 - thelancet.com
Background Identifying which individuals will develop tuberculosis (TB) remains an
unresolved problem due to few animal models and computational approaches that …

[HTML][HTML] Tuberculosis conundrum-current and future scenarios: a proposed comprehensive approach combining laboratory, imaging, and computing advances

SA Merchant, MJS Shaikh… - World Journal of Radiology, 2022 - ncbi.nlm.nih.gov
Tuberculosis (TB) remains a global threat, with the rise of multiple and extensively drug
resistant TB posing additional challenges. The International health community has set …

Cost-Effective Whole Transcriptome Sequencing Landscape and Diagnostic Potential Biomarkers in Active Tuberculosis

Z Sun, B He, Z Yang, Y Huang, Z Duan… - ACS Infectious …, 2024 - ACS Publications
Tuberculosis (TB) is a prevalent and severe infectious disease that poses a significant threat
to human health. However, it is frequently disregarded as there are not enough quick and …