SARS-CoV-2: recent variants and clinical efficacy of antibody-based therapy

DD Singh, A Sharma, HJ Lee… - Frontiers in cellular and …, 2022 - frontiersin.org
Multiple variants of SARS-CoV-2 have emerged and are now prevalent at the global level.
Currently designated variants of concern (VOCs) are B. 1.1. 7, B1. 351, P. 1, B. 1.617. 2 …

A review on evolution of emerging SARS-CoV-2 variants based on spike glycoprotein

N Ghosh, S Nandi, I Saha - International immunopharmacology, 2022 - Elsevier
Since the inception of SARS-CoV-2 in December 2019, many variants have emerged over
time. Some of these variants have resulted in transmissibility changes of the virus and may …

Breadth and function of antibody response to acute SARS-CoV-2 infection in humans

KYA Huang, TK Tan, TH Chen, CG Huang… - Plos …, 2021 - journals.plos.org
Serological and plasmablast responses and plasmablast-derived IgG monoclonal
antibodies (MAbs) have been analysed in three COVID-19 patients with different clinical …

Vaccine-escape and fast-growing mutations in the United Kingdom, the United States, Singapore, Spain, India, and other COVID-19-devastated countries

R Wang, J Chen, K Gao, GW Wei - Genomics, 2021 - Elsevier
Abstract Recently, the SARS-CoV-2 variants from the United Kingdom (UK), South Africa,
and Brazil have received much attention for their increased infectivity, potentially high …

SARS-CoV-2: evolution and emergence of new viral variants

VR Flores-Vega, JV Monroy-Molina… - Viruses, 2022 - mdpi.com
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the etiological agent
responsible for the coronavirus disease 2019 (COVID-19). The high rate of mutation of this …

[HTML][HTML] Mutations of SARS-CoV-2 and their impact on disease diagnosis and severity

L Alquraan, KH Alzoubi, SY Rababa'h - Informatics in Medicine Unlocked, 2023 - Elsevier
Numerous variations of the Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-
2), including D614G, B. 1.1. 7 (United Kingdom), B. 1.1. 28 (Brazil P1, P2), CAL. 20C …

[HTML][HTML] Structural analysis of receptor binding domain mutations in SARS-CoV-2 variants of concern that modulate ACE2 and antibody binding

D Mannar, JW Saville, X Zhu, SS Srivastava… - Cell Reports, 2021 - cell.com
The recently emerged severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) Beta
(B. 1.351) and Gamma (P. 1) variants of concern (VoCs) include a key mutation (N501Y) …

Molecular rationale for SARS-CoV-2 spike circulating mutations able to escape bamlanivimab and etesevimab monoclonal antibodies

E Laurini, D Marson, S Aulic, A Fermeglia, S Pricl - Scientific Reports, 2021 - nature.com
The purpose of this work is to provide an in silico molecular rationale of the role eventually
played by currently circulating mutations in the receptor binding domain of the SARS-CoV-2 …

[HTML][HTML] Novel SARS-CoV-2 variants: the pandemics within the pandemic

E Boehm, I Kronig, RA Neher, I Eckerle, P Vetter… - Clinical Microbiology …, 2021 - Elsevier
Background Many new variants of the severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) have been termed variants of concern/interest (VOC/I) because of the greater …

501Y.V2 and 501Y.V3 variants of SARS-CoV-2 lose binding to bamlanivimab in vitro

H Liu, P Wei, Q Zhang, Z Chen, K Aviszus, W Downing… - MAbs, 2021 - Taylor & Francis
The newly emerging variants of SARS-CoV-2 from South Africa (B. 1.351/501Y. V2) and
Brazil (P. 1/501Y. V3) have led to a higher infection rate and reinfection of COVID-19 …