Biophysical techniques include various methodologies applied in studying biological
systems at the molecular and cellular level for the drug discovery process. Various methods …

In recent years “pharmaceutical analysis” has benefited strongly from different technological
improvements in separation sciences, modern soft impact mass spectrometry methods …

Providing fundamental information on intra/intermolecular interactions and physicochemical
properties, the three-dimensional structural characterization of biological macromolecules is …

Traditionally, pharmaceutical analysis referred to the chemical analysis of drug molecules.
However, over the years, modern pharmaceutical analysis has evolved beyond this to …

Deciphering the three-dimensional structures of biomolecules, in particular,
enzymes/proteins using structural biology techniques like X-ray crystallography is an …

Over the last years, there has been an exponentially growing need and interest to bring
pharmacokinetic expertise into discovery. In order to allow a multidisciplinary selection and …

Drug research is a complex and time-consuming process. Indeed, a period of 12 to 20 years
is required from the discovery of new chemical entities (NCEs) to the marketing approval of a …

Every major biopharmaceutical company incorporates a protein crystallography unit that is
central to its structure-based drug discovery efforts. Yet these capabilities are rarely …

Recent advances in analytical chemistry, such as miniaturization, automation, robotics,
parallel separations, detection systems and chemometrics, have found interesting …

Nowadays, novel formulations, computational techniques, therapeutics agents, and
fabrication of biotechnological products with ultrafine structures are being continuously …