Respiratory fluoroquinolone monotherapy versus β-lactam plus macrolide combination therapy for hospitalized adults with community-acquired pneumonia: A …

SH Choi, A Cesar, TAC Snow, N Saleem… - International Journal of …, 2023 - Elsevier
Introduction Guidelines recommend respiratory fluoroquinolone monotherapy or β-lactam
plus macrolide combination therapy as first-line options for hospitalized adults with mild to …

[HTML][HTML] Respiratory fluoroquinolones monotherapy vs. β-lactams with or without macrolides for hospitalized community-acquired pneumonia patients: A meta-analysis

S Liu, X Tong, Y Ma, D Wang, J Huang… - Frontiers in …, 2019 - frontiersin.org
Background: The choice of empirical antibiotic treatment for patients with community-
acquired pneumonia (CAP) who are admitted to non-intensive care unit (ICU) hospital wards …

Fluoroquinolones or macrolides alone versus combined with β-lactams for adults with community-acquired pneumonia: systematic review and meta-analysis

A Raz-Pasteur, D Shasha, M Paul - International journal of antimicrobial …, 2015 - Elsevier
Community-acquired pneumonia (CAP) is a leading cause of morbidity and mortality. This
review compared two of the main treatment alternatives: quinolone or macrolide …

Respiratory fluoroquinolones for the treatment of community-acquired pneumonia: a meta-analysis of randomized controlled trials

KZ Vardakas, II Siempos, A Grammatikos, Z Athanassa… - Cmaj, 2008 - Can Med Assoc
Background: We investigated whether the use of respiratory fluoroquinolones was
associated with better clinical outcomes compared with the use of macrolides and β-lactams …

[HTML][HTML] Fluoroquinolones or macrolides in combination with β-lactams in adult patients hospitalized with community acquired pneumonia: a systematic review and …

KZ Vardakas, KK Trigkidis, ME Falagas - Clinical Microbiology and …, 2017 - Elsevier
Objective The best treatment option for hospitalized patients with community-acquired
pneumonia (CAP) has not been defined. The effectiveness of β-lactam/fluoroquinolone …

The controversy of combination vs monotherapy in the treatment of hospitalized community-acquired pneumonia

K Weiss, GS Tillotson - Chest, 2005 - Elsevier
Background The majority of community-acquired pneumonia (CAP) patients (about 80%)
will be treated as outpatients, because therapy with a single agent will work. For the …

Fluoroquinolone treatment of community-acquired pneumonia: a meta-analysis

AR Salkind, PG Cuddy… - Annals of …, 2002 - journals.sagepub.com
OBJECTIVE: To determine the role of newer fluoroquinolones (FQs) for adults with
community-acquired pneumonia (CAP) whose level of illness allows treatment with an oral …

Moxifloxacin monotherapy versus β-lactam-based standard therapy for community-acquired pneumonia: a meta-analysis of randomised controlled trials

MM An, Z Zou, H Shen, PH Gao, YB Cao… - International Journal of …, 2010 - Elsevier
The aim of this study was to compare more conclusively the efficacy and safety of
moxifloxacin, a new respiratory fluoroquinolone antibiotic, with β-lactam-based standard …

Ceftriaxone combination therapy versus respiratory fluoroquinolone monotherapy for community-acquired pneumonia: A meta-analysis

YQ Zhang, SL Zou, H Zhao, MM Zhang… - The American Journal of …, 2018 - Elsevier
Background The goal of this study was to investigate whether ceftriaxone combination
therapy is associated with better clinical outcomes than respiratory fluoroquinolone …

Macrolide-based regimens and mortality in hospitalized patients with community-acquired pneumonia: a systematic review and meta-analysis

L Asadi, WI Sligl, DT Eurich, IN Colmers… - Clinical Infectious …, 2012 - academic.oup.com
Background. Macrolides are used to treat pneumonia despite increasing antimicrobial
resistance. However, the immunomodulatory properties of macrolides may have a favorable …