Objective Personalised medicine (PM) allows treating patients based on their individual
demographic, genomic or biological characteristics for tailoring the 'right treatment for the …

Inspired by a hugely successful series entitled Treating Individuals, originally published in
The Lancet, this volume will become essential reading for any professional involved with …

Does anyone know the road from a randomized trial to personalized medicine? A review of ‘Treating
Individuals. From Randomized Page 1 ESSAY REVIEW Does anyone know the road from a …

Background Personalised medicine is a medical model that aims to provide tailor-made
prevention and treatment strategies for defined groups of individuals. The concept brings …

Penston [1, 2] has done well to draw attention to the serious problems that occur with
randomized trials as they are currently conducted in practice. Logically, it is certainly true …

Although Evidence-based medicine (EBM) and Patient-centered medicine (PCM) are often
perceived as two conflicting paradigms that speak the language of populations and the …

So-called evidence-based medicine relates to only one of these doctor functions–the
understanding of the benefits and risks of potential therapeutic strategies. Of course, all …

Results Embedded pragmatic clinical trials (PCTs) are set in routine health care, have broad
eligibility criteria, and use routinely collected electronic data. Many consider them a …

Individual Participant Data (IPD) Meta-analyses of Randomised Controlled Trials: Guidance on
Their Use | PLOS Medicine Skip to main content Advertisement PLOS Medicine Browse Current …