[HTML][HTML] Inborn errors of human B cell development, differentiation, and function
B cells develop from hematopoietic stem cells in the bone marrow. Once generated, they
serve multiple roles in immune regulation and host defense. However, their most important …
serve multiple roles in immune regulation and host defense. However, their most important …
Cytokine-mediated STAT-dependent pathways underpinning human B-cell differentiation and function
B cells are fundamental to host defence against infectious diseases; indeed, the ability of
humans to elicit robust antibody responses following exposure to foreign antigens underpins …
humans to elicit robust antibody responses following exposure to foreign antigens underpins …
[PDF][PDF] Genetic defects in B-cell development and their clinical consequences
Expression of selected genes in hematopoietic stem cells has been identified as a regulator
of differentiation of B cells in the liver and bone marrow. Moreover, naïve B cells expressing …
of differentiation of B cells in the liver and bone marrow. Moreover, naïve B cells expressing …
Human inborn errors of immunity: an expanding universe
Molecular, cellular, and clinical studies of human inborn errors of immunity have
revolutionized our understanding of their pathogenesis, considerably broadened their …
revolutionized our understanding of their pathogenesis, considerably broadened their …
B cell biology: an overview
H Eibel, H Kraus, H Sic, AK Kienzler, M Rizzi - Current allergy and asthma …, 2014 - Springer
In this review we summarize recent insights into the development of human B cells primarily
by studying immunodeficiencies. Development and differentiation of B cells can be …
by studying immunodeficiencies. Development and differentiation of B cells can be …
Somatic mutation and memory
C Berek - Current opinion in immunology, 1993 - Elsevier
The germinal center plays a crucial role in the development of the memory B cell. The
repertoire of the antigen-specific B cell is shaped in this microenvironment. Self-specific B …
repertoire of the antigen-specific B cell is shaped in this microenvironment. Self-specific B …
B-cell biology and development
K Pieper, B Grimbacher, H Eibel - Journal of Allergy and Clinical …, 2013 - Elsevier
B cells develop from hematopoietic precursor cells in an ordered maturation and selection
process. Extensive studies with many different mouse mutants provided fundamental …
process. Extensive studies with many different mouse mutants provided fundamental …
Human and mouse early B cell development: So similar but so different
J Korzhenevich, I Janowska, M van der Burg, M Rizzi - Immunology Letters, 2023 - Elsevier
Early B cell development in the bone marrow ensures the replenishment of the peripheral B
cell pool. Immature B cells continuously develop from hematopoietic stem cells, in a process …
cell pool. Immature B cells continuously develop from hematopoietic stem cells, in a process …
Non-antibody-secreting functions of B cells and their contribution to autoimmune disease
A Getahun, JC Cambier - Annual review of cell and …, 2019 - annualreviews.org
B cells play multiple important roles in the pathophysiology of autoimmune disease. Beyond
producing pathogenic autoantibodies, B cells can act as antigen-presenting cells and …
producing pathogenic autoantibodies, B cells can act as antigen-presenting cells and …
Translational Mini-Review Series on B cell subsets in disease. Reconstitution after haematopoietic stem cell transplantation–revelation of B cell developmental …
M Bemark, J Holmqvist, J Abrahamsson… - Clinical & …, 2012 - academic.oup.com
Summary OTHER ARTICLES PUBLISHED IN THIS MINI-REVIEW SERIES ON B CELL
SUBSETS IN DISEASE B cells in multiple sclerosis: drivers of disease pathogenesis and …
SUBSETS IN DISEASE B cells in multiple sclerosis: drivers of disease pathogenesis and …