A major challenge in inflammatory bowel disease (IBD) is the integration of diverse IBD data
sets to construct predictive models of IBD. We present a predictive model of the immune …

GWAS have identified> 200 risk loci for Inflammatory Bowel Disease (IBD). The majority of
disease associations are known to be driven by regulatory variants. To identify the putative …

In this review, we provide an update on genome-wide association studies (GWAS) in
inflammatory bowel disease (IBD). In addition, we summarize progress in defining the …

Genome-wide association studies (GWAS) have identified thousands of noncoding loci that
are associated with human diseases and complex traits, each of which could reveal insights …

Advancements in human genetics now poise the field to illuminate the pathophysiology of
complex genetic disease. In particular, genome-wide association studies (GWAS) have …

Inflammatory bowel disease (IBD) is a complex genetic disease that is instigated and
amplified by the confluence of multiple genetic and environmental variables that perturb the …

Background Genetic studies have been tremendously successful in identifying genomic
regions associated with a wide variety of phenotypes, although the success of these studies …

Background Human genetics and host-associated microbial communities have been
associated independently with a wide range of chronic diseases. One of the strongest …

Studies of the genetics underlying inflammatory bowel diseases have increased our
understanding of the pathways involved in both ulcerative colitis and Crohn's disease and …

OBJECTIVES: Inflammatory bowel diseases (IBD), comprised of Crohn's disease (CD) and
ulcerative colitis (UC), are characterized by a complex pathophysiology that is thought to …