Spotlight on microRNAs in allergy and asthma

J Weidner, S Bartel, A Kılıç, UM Zissler, H Renz… - Allergy, 2021 - Wiley Online Library
In past 10 years, microRNAs (miRNAs) have gained scientific attention due to their
importance in the pathophysiology of allergic diseases and their potential as biomarkers in …

Diagnostic, functional, and therapeutic roles of microRNA in allergic diseases

TX Lu, ME Rothenberg - Journal of Allergy and Clinical Immunology, 2013 - Elsevier
Allergic inflammation is accompanied by the coordinated expression of a myriad of genes
and proteins that initiate, sustain, and propagate immune responses and tissue remodeling …

MicroRNA regulation of allergic inflammation and asthma

HH Pua, KM Ansel - Current Opinion in Immunology, 2015 - Elsevier
Highlights•miRNAs regulate allergic inflammation and allergic responses.•miRNAs act
coordinately through target gene networks.•miRNAs impact diverse cellular functions in type …

MicroRNAs in allergy and asthma

A Rebane, CA Akdis - Current allergy and asthma reports, 2014 - Springer
Abstract microRNAs (miRNAs) are short, single-stranded RNA molecules that function
together with the partner proteins and cause degradation of target mRNAs or inhibit their …

Recent miRNA research in asthma

R Sharma, A Tiwari, MJ McGeachie - Current allergy and asthma reports, 2022 - Springer
Abstract Purpose of Review The study of microRNA in asthma has revealed a vibrant new
level of gene regulation underlying asthma pathology. Several miRNAs have been shown to …

MicroRNAs: Essential players in the regulation of inflammation

A Rebane, CA Akdis - Journal of Allergy and Clinical Immunology, 2013 - Elsevier
Regulation of inflammatory responses is ensured by coordinated control of gene expression
in participating immune system and tissue cells. One group of gene expression regulators …

MicroRNA profiling in asthma: potential biomarkers and therapeutic targets

E Heffler, A Allegra, G Pioggia, G Picardi… - American journal of …, 2017 - atsjournals.org
Asthma is a heterogeneous chronic inflammatory disorder in which different endotypes
contribute to define clinical inflammatory phenotypes. MicroRNAs (miRNAs) are a group of …

MicroRNAs: potential biomarkers and targets of therapy in allergic diseases?

K Specjalski, E Jassem - Archivum immunologiae et therapiae …, 2019 - Springer
MicroRNAs (miRNAs) are small non-coding RNA molecules that are 18–22 nucleotides long
and highly conserved throughout evolution. Currently, they are considered one of the …

MicroRNA

TX Lu, ME Rothenberg - Journal of allergy and clinical immunology, 2018 - Elsevier
MicroRNAs (miRNAs) are small endogenous RNAs that regulate gene-expression
posttranscriptionally. MiRNA research in allergy is expanding because miRNAs are crucial …

Not miR-ly small RNAs: big potential for microRNAs in therapy

TM Love, HF Moffett, CD Novina - Journal of allergy and clinical …, 2008 - Elsevier
RNA interference (RNAi) describes a set of natural processes in which genes are silenced
by small RNAs. RNAi has been widely used as an experimental tool that has recently …