Heart failure is a leading cause of cardiovascular morbidity and mortality. However, the
contribution of common genetic variation to heart failure risk has not been fully elucidated …

Background Heart failure (HF) is the most common potential cause of death, causing a huge
health and economic burden all over the world. So far, some impressive progress has been …

Heart failure is a major disease burden worldwide, and its incidence continues to increase
as premature deaths from other cardiovascular conditions decline. Although the overall …

Background: Heart failure (HF) is a highly prevalent disorder for which disease mechanisms
are incompletely understood. The discovery of disease-associated proteins with causal …

Heart failure (HF) is a leading cause of morbidity and mortality worldwide. A small proportion
of HF cases are attributable to monogenic cardiomyopathies and existing genome-wide …

Background: Heart failure (HF) is a morbid and heritable disorder for which the biological
mechanisms are incompletely understood. We therefore examined genetic associations with …

Heart failure is an increasingly prevalent and highly lethal disease that is most often caused
by underlying pathologies, such as myocardial infarction or hypertension, but it can also be …

This review provides the rationale for integrating genomic and protein biomarkers in the
evolving diagnosis and management of dilated cardiomyopathy (DCM) and its causal …

Background Transcriptomic studies have contributed to fundamental knowledge of
myocardial remodeling in human heart failure (HF). However, the key HF genes reported are …

Pharmacologic clinical trials for heart failure with preserved ejection fraction have been
largely unsuccessful as compared to those for heart failure with reduced ejection fraction …