Oral Administration of Probiotic Bifidobacterium breve Improves Facilitation of Hippocampal Memory Extinction via Restoration of Aberrant Higher Induction of …

T Ishii, H Furuoka, M Kaya, T Kuhara - Biomedicines, 2021 - mdpi.com
We previously reported that 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine-induced
Parkinson's disease (PD) model mice (PD mice) facilitate hippocampal memory extinction …

Neuroprotective Effects of Bifidobacterium breve CCFM1067 in MPTP-Induced Mouse Models of Parkinson's Disease

T Li, C Chu, L Yu, Q Zhai, S Wang, J Zhao, H Zhang… - Nutrients, 2022 - mdpi.com
There is mounting evidence that the microbiota–gut–brain axis (MGBA) is critical in the
pathogenesis and progression of Parkinson's disease (PD), suggesting that probiotic …

Therapeutic potential of Bifidobacterium breve strain A1 for preventing cognitive impairment in Alzheimer's disease

Y Kobayashi, H Sugahara, K Shimada, E Mitsuyama… - Scientific reports, 2017 - nature.com
It has previously been shown that the consumption of probiotics may have beneficial effects
not only on peripheral tissues but also on the central nervous system and behavior via the …

Probiotic Bifidobacterium breve MCC1274 Mitigates Alzheimer's Disease-Related Pathologies in Wild-Type Mice

M Abdelhamid, C Zhou, CG Jung, M Michikawa - Nutrients, 2022 - mdpi.com
Probiotics improve brain function, including memory and cognition, via the microbiome–gut–
brain axis. Oral administration of Bifidobacterium breve MCC1274 (B. breve MCC1274) …

Probiotics treatment improves hippocampal dependent cognition in a rodent model of Parkinson's disease

C Xie, AA Prasad - Microorganisms, 2020 - mdpi.com
Parkinson's disease (PD) is a neurological disorder with motor dysfunction and a number of
psychiatric symptoms. Symptoms such as anxiety and cognitive deficits emerge prior to …

Neuroprotective Effects of Bifidobacterium animalis subsp. lactis NJ241 in a Mouse Model of Parkinson's Disease: Implications for Gut Microbiota and PGC-1α

Y Dong, Y Qi, J Chen, S Han, W Su, X Ma, Y Yu… - Molecular …, 2024 - Springer
Intestinal dysbiosis plays a critical role in the pathogenesis of Parkinson's disease (PD), and
probiotics have emerged as potential modulators of central nervous system function through …

Supplementation of probiotic Bifidobacterium breve Bif11 reverses neurobehavioural deficits, inflammatory changes and oxidative stress in Parkinson's disease model

S Valvaikar, B Vaidya, S Sharma, M Bishnoi… - Neurochemistry …, 2024 - Elsevier
Human gut microbiota are thought to affect different physiological processes in the body,
including brain functions. Gut dysbiosis has been linked to the progression of Parkinson's …

Probiotics mixture increases butyrate, and subsequently rescues the nigral dopaminergic neurons from MPTP and rotenone-induced neurotoxicity

S Srivastav, S Neupane, S Bhurtel, N Katila… - The Journal of …, 2019 - Elsevier
Microbiota in the gut affect brain physiology via various pathways, and dysbiosis seems to
play a role in the pathogenesis of Parkinson's disease (PD). Probiotics showed pleiotropic …

Bifidobacterium breve HNXY26M4 Attenuates Cognitive Deficits and Neuroinflammation by Regulating the Gut–Brain Axis in APP/PS1 Mice

G Zhu, J Zhao, G Wang, W Chen - Journal of Agricultural and Food …, 2023 - ACS Publications
Alzheimer's disease (AD) is a neurodegenerative disease, pathological markers of which
are amyloid plaques and neurofibrillary tangles. As a key node of gut–brain axis, gut …

Administration of Bifidobacterium breve Improves the Brain Function of Aβ1-42-Treated Mice via the Modulation of the Gut Microbiome

G Zhu, J Zhao, H Zhang, W Chen, G Wang - Nutrients, 2021 - mdpi.com
Psychobiotics are used to treat neurological disorders, including mild cognitive impairment
(MCI) and Alzheimer's disease (AD). However, the mechanisms underlying their …