ME Alarcón‐Riquelme, JT Ziegler… - Arthritis & …, 2016 - Wiley Online Library
Objective Systemic lupus erythematosus (SLE) is a chronic autoimmune disease with a strong genetic component. We undertook the present work to perform the first genome‐wide …
Systemic lupus erythematosus (SLE), a worldwide autoimmune disease with high heritability, shows differences in prevalence, severity and age of onset among different …
DL Morris, Y Sheng, Y Zhang, YF Wang, Z Zhu… - Nature …, 2016 - nature.com
Systemic lupus erythematosus (SLE; OMIM 152700) is a genetically complex autoimmune disease. Genome-wide association studies (GWASs) have identified more than 50 loci as …
JW Han, HF Zheng, Y Cui, LD Sun, DQ Ye, Z Hu… - Nature …, 2009 - nature.com
We performed a genome-wide association study (GWAS) of systemic lupus erythematosus (SLE) in a Chinese Han population by genotyping 1,047 cases and 1,205 controls using …
Systemic lupus erythematosus (SLE) is a common systemic autoimmune disease with complex etiology but strong clustering in families (λ S=∼ 30). We performed a genome-wide …
MD Catalina, P Bachali, AE Yeo, NS Geraci, MA Petri… - Jci Insight, 2020 - ncbi.nlm.nih.gov
Gene expression signatures can stratify patients with heterogeneous diseases, such as systemic lupus erythematosus (SLE), yet understanding the contributions of ancestral …
PS Ramos, LA Criswell, KL Moser, ME Comeau… - PLoS …, 2011 - journals.plos.org
In spite of the well-known clustering of multiple autoimmune disorders in families, analyses of specific shared genes and polymorphisms between systemic lupus erythematosus (SLE) …
Systemic lupus erythematosus (SLE) is a genetically complex autoimmune disease characterized by loss of immune tolerance to nuclear and cell surface antigens. Previous …
The genome-wide association study is a free-hypothesis approach based on screening of thousands or even millions of genetic variants distributed throughout the whole human …