Tauopathies are classified according to whether tau deposits predominantly contain tau
isoforms with three or four repeats of the microtubule-binding domain. Those in which four …

Tau is a microtubule-associated protein with versatile functions in the dynamic assembly of
the neuronal cytoskeleton. Four-repeat (4R-) tauopathies are a group of neurodegenerative …

Four-repeat tauopathies are a neurodegenerative disease characterized by brain
parenchymal accumulation of a specific isoform of the protein tau, which gives rise to a wide …

The majority of neurodegenerative diseases are characterized by the deposition of insoluble
protein in cells of the neuromuscular system. Advances in molecular neuropathology have …

Tauopathies are a diverse group of diseases featuring progressive dying-back
neurodegeneration of specific neuronal populations in association with accumulation of …

Tauopathies are clinically, morphologically and biochemically heterogeneous
neurodegenerative diseases characterized by the deposition of abnormal tau protein in the …

Tau is a microtubule-associated binding protein in the nervous system that is known for its
role in stabilizing microtubules throughout the nerve cell. It accumulates as β-sheet-rich …

Abundant neurofibrillary lesions made of hyperphosphorylated microtubule‐associated
protein tau constitute one of the defining neuropathological features of Alzheimer's disease …

Tauopathies are a class of neurodegenerative disorders characterized by neuronal and/or
glial inclusions composed of the microtubule-binding protein, tau. Several lines of evidence …

Abundant neurofibrillary lesions made of abnormal and hyperphosphorylated microtubule‐
associated protein tau constitute one of the defining neuropathological features of …