CircUGGT2 facilitates progression and cisplatin resistance of bladder cancer through nonhomologous end-joining pathway

F Lyu, S Huang, Z Yan, Q He, C Liu, L Cheng, Y Cong… - Cellular …, 2024 - Elsevier
The development of resistance to cisplatin (CDDP) in bladder cancer presents a notable
obstacle, with indications pointing to the substantial role of circular RNAs (circRNAs) in this …

EIF4A3-mediated biogenesis of circSTX6 promotes bladder cancer metastasis and cisplatin resistance

W Wei, K Liu, X Huang, S Tian, H Wang… - Journal of Experimental …, 2024 - Springer
Background Cisplatin (CDDP)-based chemotherapy is a standard first-line treatment for
metastatic bladder cancer (BCa) patients, and chemoresistance remains a major challenge …

[HTML][HTML] Circular RNA CircHIPK3 promotes gemcitabine sensitivity in bladder cancer

F Xie, N Zhao, H Zhang, D Xie - Journal of Cancer, 2020 - ncbi.nlm.nih.gov
Purpose: Recent studies showed circular RNA (circRNA) played important regulatory roles
in tumors, including genesis of chemotherapy resistance. In this study, the role of circHIPK3 …

CircLIFR synergizes with MSH2 to attenuate chemoresistance via MutSα/ATM-p73 axis in bladder cancer

H Zhang, X Xiao, W Wei, C Huang, M Wang, L Wang… - Molecular cancer, 2021 - Springer
Background Cisplatin (CDDP) has become a standard-of-care treatment for muscle-invasive
bladder cancer (MIBC), while chemoresistance remains a major challenge. Accumulating …

N6-methyladenosine-modified circPLPP4 sustains cisplatin resistance in ovarian cancer cells via PIK3R1 upregulation

H Li, R Lin, Y Zhang, Y Zhu, S Huang, J Lan, N Lu… - Molecular Cancer, 2024 - Springer
Background Cisplatin (CDDP) is the first-line chemotherapeutic strategy to treat patients with
ovarian cancer (OC). The development of CDDP resistance remains an unsurmountable …

Research progress on the functions and mechanism of circRNA in cisplatin resistance in tumors

Q Mu, Y Lv, C Luo, X Liu, C Huang, Y Xiu… - Frontiers in …, 2021 - frontiersin.org
Cisplatin is a common chemotherapeutic drug that has been used to treat of numerous
tumors, including testicular, lung, bladder, ovarian, liver and head and neck cancers …

circUBAP2 inhibits cisplatin resistance in gastric cancer via miR-300/KAT6B axis

W Cheng, P Luan, X Jin - Anti-Cancer Drugs, 2023 - journals.lww.com
Circular RNAs play an important role in regulating cisplatin (CDDP) resistance in gastric
cancer (GC). The aim of this study was to examine the role and downstream regulation …

A novel circular RNA circFN1 enhances cisplatin resistance in gastric cancer via sponging miR‐182‐5p

X Huang, Q Zhang, H Hu, Y Jin, A Zeng… - Journal of Cellular …, 2021 - Wiley Online Library
Cisplatin (CDDP) is commonly used for gastric cancer (GC) chemotherapy. However, after
several CDDP‐based treatment cycles, patients always acquire chemotherapy resistance …

CircFAM114A2 Promotes Cisplatin Sensitivity via miR-222-3p/P27 and miR-146a-5p/P21 Cascades in Urothelial Carcinoma

J Lv, Z Zhou, J Wang, X Yang, H Yu, J Han… - Frontiers in …, 2021 - frontiersin.org
Introduction Circular RNAs (circRNAs) are non-coding RNAs that have the structure of a
covalently closed loop. Increasing data have proven that circRNAs can influence the …

circANKRD17 (has_circ_0007883) confers paclitaxel resistance of ovarian cancer via interacting with FUS to stabilize FOXR2

YX Liang, LL Zhang, L Yang - Molecular and Cellular Biochemistry, 2023 - Springer
Emerging numbers of endogenous circular RNAs (circRNAs) have gained much attention to
serve as essential regulators in the carcinogenesis of human cancers. Unfortunately, the …