Background Genetic data are known to harbor information about human demographics, and
genotyping data are commonly used for capturing ancestry information by leveraging …

Here we report three epigenome-wide association studies (EWAS) of DNA methylation on
self-reported race, global genetic ancestry, and local genetic ancestry in admixed Americans …

Abstract Epigenome-Wide Association Study (EWAS) has become an effective strategy to
explore epigenetic basis of complex traits. Over the past decade, a large amount of …

GLINT is a user-friendly command-line toolset for fast analysis of genome-wide DNA
methylation data generated using the Illumina human methylation arrays. GLINT, which …

DNA methylation is an epigenetic mark that has suspected regulatory roles in a broad range
of biological processes and diseases. The technology is now available for studying DNA …

Metastable and somatically heritable patterns of DNA methylation provide an important level
of genomic regulation. In this article, we review methods for analyzing these genome-wide …

The haploid human genome contains approximately 29 million CpGs that exist in a
methylated, hydroxymethylated or unmethylated state, collectively referred to as the DNA …

Genomic DNA methylation profiles exhibit substantial variation within the human population,
with important functional implications for gene regulation. So far little is known about the …

DNA methylation plays a critical role in the regulation of gene expression. The ability to
access the methylation status for a large number of genes or the entire genome should …

Recent evidence suggests that DNA methylation changes may underlie numerous complex
traits and diseases. The advent of commercial, array-based methods to interrogate DNA …