Functional delivery of mRNA has high clinical potential. Previous studies established that mRNAs can be delivered to cells in vitro and in vivo via RNA-loaded lipid nanoparticles …
KH Yoo, N Thapa, BJ Kim, JO Lee… - Molecular …, 2022 - spandidos-publications.com
Abstract Coronavirus disease 2019 (COVID‑19) is a global pandemic that can have a long‑ lasting impact on public health if not properly managed. Ongoing vaccine development trials …
Z Troyer, N Alhusaini, CO Tabler… - Journal of …, 2021 - Wiley Online Library
In late 2019, a novel coronavirus named severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) emerged in Wuhan, China. SARS‐CoV‐2 and the disease it causes …
Z Wang, KD Popowski, D Zhu… - Nature biomedical …, 2022 - nature.com
The first two mRNA vaccines against infection by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that were approved by regulators require a cold chain and …
In this study we profiled vaccine-induced polyclonal antibodies as well as plasmablast- derived mAbs from individuals who received SARS-CoV-2 spike mRNA vaccine. Polyclonal …
Simple Summary Extracellular vesicles (EVs) allow cell-to-cell communication and can induce a strong immune response, by presenting antigens. EVs can be engineered to …
P Santos, F Almeida - Frontiers in immunology, 2021 - frontiersin.org
Extracellular vesicles (EVs) are released by most cell types as part of an intracellular communication system in crucial processes such as inflammation, cell proliferation, and …
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is responsible for the COVID-19 pandemic. Neutralizing Abs target the receptor binding domain of the spike (S) …
Objectives Nearly three years into the pandemic, SARS-CoV-2 infections are occurring in vaccinated and naturally infected populations. While humoral and cellular responses in …