Influence of omega 3 and 6 fatty acids on human meibomian gland epithelial cells

Y Liu, WR Kam, DA Sullivan - Cornea, 2016 - journals.lww.com
Purpose: Oral supplementation with omega 3 (ω-3) and/or 6 (ω-6) fatty acids (FAs) has been
reported to alleviate the signs and symptoms of dry eye disease and to improve the …

[HTML][HTML] The role of omega-3 dietary supplementation in blepharitis and meibomian gland dysfunction (an AOS thesis)

MS Macsai - Transactions of the American Ophthalmological …, 2008 - ncbi.nlm.nih.gov
Purpose Blepharitis and meibomian gland dysfunction (MGD) are common sources of
complaints from patients. To evaluate the effect on ocular symptoms, ocular findings, and …

In vitro effects of docosahexaenoic and eicosapentaenoic acid on human meibomian gland epithelial cells

U Hampel, M Krüger, C Kunnen, F Garreis… - Experimental eye …, 2015 - Elsevier
To investigate the effect of ω-3 fatty acids on human meibomian gland epithelial cells
(HMGECs, cell line) in vitro. HMGECs were stimulated with docosahexaenoic acid (DHA) or …

Pilot, prospective, randomized, double-masked, placebo-controlled clinical trial of an omega-3 supplement for dry eye

JC Wojtowicz, I Butovich, E Uchiyama, J Aronowicz… - Cornea, 2011 - journals.lww.com
Purpose: To investigate the potential effect of dietary supplementation with omega-3 fatty
acid on lipid composition of meibum, aqueous tear evaporation, and tear volume in patients …

Human meibum and tear film derived (O-acyl)-omega-hydroxy fatty acids in meibomian gland dysfunction

S Khanal, W Ngo, KK Nichols, L Wilson, S Barnes… - The ocular …, 2021 - Elsevier
Purpose The molecular basis of the tear film and lipid layer alterations in meibomian gland
dysfunction (MGD) is unknown. This study aimed to identify and compare (O-acyl)-omega …

[HTML][HTML] Topical omega-3 fatty acids eyedrops in the treatment of dry eye and ocular surface disease: a systematic review

B Paik, L Tong - International Journal of Molecular Sciences, 2022 - mdpi.com
Dry eye is a common inflammatory condition of the ocular surface. While oral omega-3
supplementation for its treatment has been extensively studied, recent large-scale studies …

A randomized, double-masked study to evaluate the effect of omega-3 fatty acids supplementation in meibomian gland dysfunction

A Oleñik, I Jiménez-Alfaro… - … interventions in aging, 2013 - Taylor & Francis
Background Dysfunction of the meibomian gland (MG) is among the most frequent causes of
ophthalmological symptoms. The inflammation seen in meibomian gland dysfunction (MGD) …

[HTML][HTML] Relation between dietary essential fatty acid intake and dry eye disease and meibomian gland dysfunction in postmenopausal women

JF Ziemanski, LR Wolters, L Jones-Jordan… - American journal of …, 2018 - Elsevier
Purpose To evaluate the relationship between omega-3 (n-3) and omega-6 (n-6) fatty acids
with dry eye disease (DED) and meibomian gland dysfunction (MGD). Design Cross …

Differential effects of dietary cholesterol and triglycerides on the lipid homeostasis in Meibomian glands

IA Butovich, A Wilkerson, S Yuksel - The Journal of steroid biochemistry and …, 2021 - Elsevier
Exocrine Meibomian glands (MG) play a central role in the ocular surface physiology by
producing meibum–a lipid secretion composed of cholesteryl esters (CE), cholesterol (Chl) …

[HTML][HTML] Effect of oral re-esterified omega-3 nutritional supplementation on dry eyes

AT Epitropoulos, ED Donnenfeld, ZA Shah, EJ Holland… - Cornea, 2016 - journals.lww.com
Purpose: To assess the effect of oral re-esterified omega-3 fatty acids on tear osmolarity,
matrix metalloproteinase-9 (MMP-9), tear break-up time (TBUT), Ocular Surface Disease …