Background Cancer stem cells (CSCs) can proliferate and self-renew extensively due to
their ability to express anti-apoptotic and drug resistant proteins, thus sustaining tumor …

Background & Aims Tumor-microenvironment factors and cancer stem cells (CSCs) play a
critical role in the aggressiveness of pancreatic cancer (PC). However, the degree to which …

Objectives Gemcitabine is a standard treatment for advanced pancreatic cancer patients but
can cause chemoresistance during treatment. The chemoresistant cells have features of …

Resveratrol (trans-3, 4', 5-trihydroxystilbene), a natural polyphenolic compound detected in
grapes, berries, and peanuts, possesses a wide spectrum of pharmacological properties …

Resveratrol and quercetin are phytochemicals that are found in a variety of plants. The aim
of this study was to investigate the effect of resveratrol and quercetin on epithelial …

Activation of pancreatic stellate cells (PSCs) initiates pancreatic fibrosis in chronic
pancreatitis and furnishes a niche that enhances the malignancy of pancreatic cancer cells …

Background Much attention has been recently focused on the role of cancer stem cells
(CSCs) in the initiation and progression of solid malignancies. Since CSCs are able to …

In the past few years, there have been significant advances in the research on cancer stem
cells (CSCs). The emerging evidences have demonstrated that CSCs and epithelial …

Resveratrol, a natural polyphenolic compound, is abundantly found in plant foods and has
been extensively studied for its anti-cancer properties. Given the important role of CSCs …

Purpose: To investigate the effect and possible mechanisms of resveratrol on pancreatic
cancer cells in vitro. Methods: After being treated with resveratrol, cell viability, cell cycle …