Emodin induces apoptosis of human cervical cancer cells through poly (ADP-ribose) polymerase cleavage and activation of caspase-9

G Srinivas, RJ Anto, P Srinivas, S Vidhyalakshmi… - European journal of …, 2003 - Elsevier
Emodin (1, 3, 8-trihydroxy-6-methylanthraquinone) is an active herbal component
traditionally used in China for treating various ailments. Emodin exerts antiproliferative …

Emodin regulates apoptotic pathway in human liver cancer cells

JQ Yu, W Bao, JC Lei - Phytotherapy Research, 2013 - Wiley Online Library
Emodin, a natural anthraquinone, has been reported to possess antiproliferative effects in
many cancer cell lines. However, anticancer mechanism against human liver cancer …

Emodin-induced apoptosis in human breast cancer BCap-37 cells through the mitochondrial signaling pathway

Z Huang, G Chen, P Shi - Archives of pharmacal research, 2008 - Springer
Emodin, a natural anthraquinone compound isolated from the rhizome of rhubarb, is
reported to suppress the growth of tumor in many clinical situations. In this study, we focused …

Antitumor effects of emodin on LS1034 human colon cancer cells in vitro and in vivo: Roles of apoptotic cell death and LS1034 tumor xenografts model

YS Ma, SW Weng, MW Lin, CC Lu, JH Chiang… - Food and Chemical …, 2012 - Elsevier
Emodin, an active natural anthraquinone derivative, is found in the roots and rhizomes of
numerous Chinese medicinal herbs and exhibits anticancer effects on many types of human …

Anti-tumor effect of emodin on gynecological cancer cells

Y Wang, H Yu, J Zhang, X Ge, J Gao, Y Zhang, G Lou - Cellular Oncology, 2015 - Springer
Purpose Although an anti-tumor effect of emodin has been reported before, its effect on
human gynecological cancer cells has so far not been studied. Here, we assessed the effect …

[HTML][HTML] Emodin induces apoptosis of human cervical cancer hela cells via intrinsic mitochondrial and extrinsic death receptor pathway

W Yaoxian, Y Hui, Z Yunyan, L Yanqin, G Xin… - Cancer cell …, 2013 - Springer
Background Emodin is a natural anthraquinone derivative isolated from the Rheum
palmatum L. Aim: The aim of the present study was to investigate the effect of emodin on the …

Emodin induces apoptosis of human tongue squamous cancer SCC-4 cells through reactive oxygen species and mitochondria-dependent pathways

SY Lin, WW Lai, CC Ho, FS Yu, GW Chen… - Anticancer …, 2009 - ar.iiarjournals.org
Emodin was isolated from Rheum palmatum L. and exhibits an anticancer effect on human
cancer cell lines, however, the molecular mechanisms of emodin-mediated apoptosis in …

Molecular mechanism of emodin action: transition from laxative ingredient to an antitumor agent

G Srinivas, S Babykutty… - Medicinal research …, 2007 - Wiley Online Library
Anthraquinones represent a large family of compounds having diverse biological properties.
Emodin (1, 3, 8‐trihydroxy‐6‐methylanthraquinone) is a naturally occurring anthraquinone …

Anti-tumor activity of emodin against human chronic myelocytic leukemia K562 cell lines in vitro and in vivo

W Chun-Guang, Y Jun-Qing, L Bei-Zhong… - European journal of …, 2010 - Elsevier
Emodin (1, 3, 8-trihydroxy-6-methyl-anthraquinone), a natural anthraquinone derivative
isolated from Rheum palmatum L, has been reported to exhibit anti-cancer effect on several …

Emodin induces apoptosis in human promyeloleukemic HL-60 cells accompanied by activation of caspase 3 cascade but independent of reactive oxygen species …

YC Chen, SC Shen, WR Lee, FL Hsu, HY Lin… - Biochemical …, 2002 - Elsevier
Emodin (1, 3, 8-trihydroxy-6-methylanthraquinone) is an active constituent of Rheum
palmatum, and showed inhibitory activity on lipopolysaccharide-induced NO production in …