mRNA booster immunization elicits potent neutralizing serum activity against the SARS-CoV-2 Omicron variant

H Gruell, K Vanshylla, P Tober-Lau, D Hillus… - Nature medicine, 2022 - nature.com
The Omicron variant of SARS-CoV-2 is causing a rapid increase in infections across the
globe. This new variant of concern carries an unusually high number of mutations in key …

[HTML][HTML] SARS-CoV-2 Omicron neutralization by therapeutic antibodies, convalescent sera, and post-mRNA vaccine booster

S Lusvarghi, SD Pollett, SN Neerukonda, W Wang… - BioRxiv, 2021 - ncbi.nlm.nih.gov
The rapid spread of the highly contagious Omicron variant of SARS-CoV-2 along with its
high number of mutations in the spike gene has raised alarm about the effectiveness of …

mRNA-based COVID-19 vaccine boosters induce neutralizing immunity against SARS-CoV-2 Omicron variant

WF Garcia-Beltran, KJS Denis, A Hoelzemer, EC Lam… - Cell, 2022 - cell.com
Recent surveillance has revealed the emergence of the SARS-CoV-2 Omicron variant (BA.
1/B. 1.1. 529) harboring up to 36 mutations in spike protein, the target of neutralizing …

mRNA-1273 and BNT162b2 mRNA vaccines have reduced neutralizing activity against the SARS-CoV-2 omicron variant

VV Edara, KE Manning, M Ellis, L Lai, KM Moore… - Cell Reports …, 2022 - cell.com
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) omicron variant
emerged in November 2021 and consists of several mutations within the spike. We use …

[HTML][HTML] Neutralizing antibodies against the SARS-CoV-2 Delta and Omicron variants following heterologous CoronaVac plus BNT162b2 booster vaccination

E Pérez-Then, C Lucas, VS Monteiro, M Miric… - Nature medicine, 2022 - nature.com
The recent emergence of the SARS-CoV-2 Omicron variant is raising concerns because of
its increased transmissibility and its numerous spike mutations, which have the potential to …

Heterologous immunization with inactivated vaccine followed by mRNA-booster elicits strong immunity against SARS-CoV-2 Omicron variant

F Zuo, H Abolhassani, L Du, A Piralla… - Nature …, 2022 - nature.com
The recent emergence of the Omicron variant has raised concerns on vaccine efficacy and
the urgent need to study more efficient vaccination strategies. Here we observed that an …

Neutralizing antibodies against the SARS-CoV-2 Omicron variant BA. 1 following homologous and heterologous CoronaVac or BNT162b2 vaccination

SMS Cheng, CKP Mok, YWY Leung, SS Ng… - Nature medicine, 2022 - nature.com
The Omicron variant is rapidly becoming the dominant SARS-CoV-2 virus circulating
globally. It is important to define reductions in virus neutralizing activity in the serum of …

[HTML][HTML] Booster of mRNA-1273 vaccine reduces SARS-CoV-2 Omicron escape from neutralizing antibodies

NA Doria-Rose, X Shen, SD Schmidt, S O'Dell… - MedRxiv, 2021 - medrxiv.org
The Omicron variant of SARS-CoV-2 is raising concerns because of its increased
transmissibility and potential for reduced susceptibility to antibody neutralization. To assess …

[HTML][HTML] Booster of mRNA-1273 strengthens SARS-CoV-2 Omicron neutralization

NA Doria-Rose, X Shen, SD Schmidt, S O'Dell… - MedRxiv, 2021 - ncbi.nlm.nih.gov
The Omicron variant of SARS-CoV-2 is raising concerns because of its increased
transmissibility and potential for reduced susceptibility to antibody neutralization. To assess …

Three exposures to the spike protein of SARS-CoV-2 by either infection or vaccination elicit superior neutralizing immunity to all variants of concern

PR Wratil, M Stern, A Priller, A Willmann, G Almanzar… - Nature medicine, 2022 - nature.com
Infection-neutralizing antibody responses after severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) infection or coronavirus disease 2019 vaccination are an …