[HTML][HTML] Environmental risk factors for schizophrenia and bipolar disorder and their relationship to genetic risk: current knowledge and future directions

N Robinson, SE Bergen - Frontiers in genetics, 2021 - frontiersin.org
Schizophrenia (SZ) and bipolar disorder (BD) are severe psychiatric disorders which result
from complex interplay between genetic and environmental factors. It is well-established that …

Gene-environment interactions in schizophrenia: a literature review

MH Wahbeh, D Avramopoulos - Genes, 2021 - mdpi.com
Schizophrenia is a devastating mental illness with a strong genetic component that is the
subject of extensive research. Despite the high heritability, it is well recognized that non …

The ecogenetics of schizophrenia: a review

J van Os, M Marcelis - Schizophrenia Research, 1998 - Elsevier
Schizophrenia is generally thought to arise as a result of interactions between genetic
vulnerability and environmental risk factors. However, research methods to actually …

Non-genetic factors in schizophrenia

SA Stilo, RM Murray - Current psychiatry reports, 2019 - Springer
Abstract Purpose of Review We review recent developments on risk factors in
schizophrenia. Recent Findings The way we think about schizophrenia today is profoundly …

Etiology in psychiatry: embracing the reality of poly‐gene‐environmental causation of mental illness

R Uher, A Zwicker - World Psychiatry, 2017 - Wiley Online Library
Intriguing findings on genetic and environmental causation suggest a need to reframe the
etiology of mental disorders. Molecular genetics shows that thousands of common and rare …

Examining the independent and joint effects of molecular genetic liability and environmental exposures in schizophrenia: results from the EUGEI study

S Guloksuz, LK Pries, P Delespaul, G Kenis… - World …, 2019 - Wiley Online Library
Schizophrenia is a heritable complex phenotype associated with a background risk
involving multiple common genetic variants of small effect and a multitude of environmental …

Identifying gene-environment interactions in schizophrenia: contemporary challenges for integrated, large-scale investigations

European Network of National Networks … - Schizophrenia …, 2014 - academic.oup.com
Recent years have seen considerable progress in epidemiological and molecular genetic
research into environmental and genetic factors in schizophrenia, but methodological …

[HTML][HTML] Gene–environment interactions in severe mental illness

R Uher - Frontiers in psychiatry, 2014 - frontiersin.org
Severe mental illness (SMI) is a broad category that includes schizophrenia, bipolar
disorder, and severe depression. Both genetic disposition and environmental exposures …

Interactions between variation in candidate genes and environmental factors in the etiology of schizophrenia and bipolar disorder: a systematic review

B Misiak, F Stramecki, Ł Gawęda, K Prochwicz… - Molecular …, 2018 - Springer
Schizophrenia and bipolar disorder (BD) are complex and multidimensional disorders with
high heritability rates. The contribution of genetic factors to the etiology of these disorders is …

Schizophrenia: an update and review

J Austin - Journal of Genetic Counseling, 2005 - Wiley Online Library
Schizophrenia is a common complex disorder characterized by psychosis, cognitive
dysfunction and negative symptoms, whose etiology involves interactions between both …