Antibiotic use during pregnancy increases offspring asthma severity in a dose‐dependent manner

MM Alhasan, AM Cait, MM Heimesaat, M Blaut… - Allergy, 2020 - Wiley Online Library
Background The use of antibiotics during pregnancy is associated with increased allergic
asthma risk in the offspring, and given that approximately 25% of pregnant women are …

Prenatal antibiotic exposure and childhood asthma: a population-based study

K Loewen, B Monchka, SM Mahmud… - European Respiratory …, 2018 - Eur Respiratory Soc
Antibiotic use during infancy alters gut microbiota and immune development and is
associated with an increased risk of childhood asthma. The impact of prenatal antibiotic …

Dose, timing, and spectrum of prenatal antibiotic exposure and risk of childhood asthma

KN Turi, T Gebretsadik, T Ding, A Abreo… - Clinical Infectious …, 2021 - academic.oup.com
Background The potential for prenatal antibiotic exposure to influence asthma risk is not
clear. We aimed to determine the effect of timing, dose, and spectrum of prenatal antibiotic …

Antibiotic use during pregnancy and asthma in preschool children: the influence of confounding

B Mulder, KB Pouwels… - Clinical & …, 2016 - Wiley Online Library
Background A recent study suggested that early‐life intestinal microbiota may play an
important role in the development of childhood asthma, indicating that antibiotics taken …

[HTML][HTML] Periconceptional and gestational exposure to antibiotics and childhood asthma

S Chu, H Yu, Y Chen, Q Chen, B Wang, J Zhang - PloS one, 2015 - journals.plos.org
Background Previous studies suggest that maternal antibiotics exposure during pregnancy
may increase the risk of childhood asthma, but the results were inconsistent. Furthermore …

Relationship between prenatal antibiotic use and asthma in at-risk children

B Lapin, J Piorkowski, D Ownby, S Freels… - Annals of Allergy …, 2015 - Elsevier
Background Asthma prevalence has doubled in developed countries during the past 30
years. Pre-and perinatal events are essential in shaping the development of the immune …

Prenatal and post‐natal exposure to antibiotics and risk of asthma in childhood

J Metsälä, A Lundqvist, LJ Virta, M Kaila… - Clinical & …, 2015 - Wiley Online Library
Background Evidence on the association between post‐natal exposure to antibiotics and the
development of asthma is extensive, but inconsistent and even less is known about prenatal …

[HTML][HTML] The maternal diet, gut bacteria, and bacterial metabolites during pregnancy influence offspring asthma

LEK Gray, M O'Hely, S Ranganathan, PD Sly… - Frontiers in …, 2017 - frontiersin.org
This review focuses on the current evidence that maternal dietary and gut bacterial
exposures during pregnancy influence the developing fetal immune system and subsequent …

[HTML][HTML] Childhood inflammatory and metabolic disease following exposure to antibiotics in pregnancy, antenatally, intrapartum and neonatally

RF Lamont, BM Luef, JS Jørgensen - F1000Research, 2020 - ncbi.nlm.nih.gov
Background: There are concerns that the use of antibiotics before, during or immediately
after pregnancy may have adverse effects on the neonatal gut microbiome and adversely …

Maternal propensity for infections and risk of childhood asthma: a registry-based cohort study

J Stokholm, A Sevelsted, K Bønnelykke… - The Lancet Respiratory …, 2014 - thelancet.com
Background Maternal use of antibiotics during pregnancy has been associated with the
development of asthmatic disorders in the offspring. The human microbiome has been …