Cytokine dysregulation is believed to play a key role in the remodeling of the immune
system at older age, with evidence pointing to an inability to fine-control systemic …

Highlights•Elderly people commonly show signs of low level systemic inflammation.•Causes
include presence of senescent cells, chronic infections and obesity.•Systemic inflammation …

Chronic inflammation is the common pathological basis for such age-associated diseases
as cardiovascular disease, diabetes, cancer and Alzheimer's disease. A multitude of bodily …

Recent scientific studies have advanced the notion of chronic inflammation as a major risk
factor underlying aging and age-related diseases. In this review, low-grade, unresolved …

Nowadays, people are living much longer than they used to do, however they are not free
from ageing. Ageing, an inexorable intrinsic process that affects all cells, tissues, organs and …

Acute inflammation is a physiological response to injury or infection, with a cascade of steps
that ultimately lead to the recruitment of immune cells to clear invading pathogens and heal …

Abstract The National Institutes of Health (NIH) Geroscience Interest Group (GSIG)
sponsored workshop, The Role of Inflammation in Age-Related Disease, was held …

The process of maintaining life for the individual is a constant struggle to preserve his/her
integrity. This can come at a price when immunity is involved, namely systemic inflammation …

Aging is a gradual, continuous series of natural changes in biological, physiological,
immunological, environmental, psychological, behavioral, and social processes. Aging …

Biological aging is characterized by a chronic low-grade inflammation level. This chronic
phenomenon has been named “inflamm-aging” and is a highly significant risk factor for …