Age-related changes in cortical volumes are well established but relatively few studies
probed its constituents, surface area (SA) and thickness (TH). Here we analyzed 10-year, 3 …

Regional cortical brain volume is the product of surface area and thickness. These
measures exhibit partially distinct trajectories of change across the brain's cortex in older …

Human cortical thickness and surface area are genetically independent, emerge through
different neurobiological events during development, and are sensitive to different clinical …

The thickness and surface area of cortex are genetically distinct aspects of brain structure,
and may be affected differently by age. However, their potential to differentially predict age …

Although it is recognized that the human cortex thins with age, longitudinal estimates of
thinning patterns specific to healthy young-old age (< 75 years) individuals are lacking …

This study investigated whether relationships between age and measures of gray matter in
the brain differed across the lifespan and by years of education. The hypothesis is that year …

Abstract Magnetic Resonance Imaging (MRI) studies have shown that cortical volume
declines with age. Although volume is a multiplicative measure consisting of thickness and …

We aimed to investigate associations between regional cortical thickness and rate of decline
over time in 4 cognitive domains in patients with subjective cognitive decline (SCD). We …

Background/Aims: Atrophy in both grey and white matter is found in normal aging. The
prefrontal cortex and the frontal lobe white matter are thought to be the most affected …

Prior studies suggest that relationships between regional cortical thickness and domain-
specific cognitive performance can be mediated by the relationship between global cortical …