[HTML][HTML] mRNA-based therapeutics: powerful and versatile tools to combat diseases

S Qin, X Tang, Y Chen, K Chen, N Fan… - Signal transduction and …, 2022 - nature.com
The therapeutic use of messenger RNA (mRNA) has fueled great hope to combat a wide
range of incurable diseases. Recent rapid advances in biotechnology and molecular …

mRNA nanomedicine: Design and recent applications

LJ Kubiatowicz, A Mohapatra, N Krishnan… - …, 2022 - Wiley Online Library
The rational design and application of mRNA‐based medicine have recently yielded some
key successes in the clinical management of human diseases. mRNA technology allows for …

The challenge and prospect of mRNA therapeutics landscape

Y Weng, C Li, T Yang, B Hu, M Zhang, S Guo… - Biotechnology …, 2020 - Elsevier
Messenger RNA (mRNA)-based therapeutics hold the potential to cause a major revolution
in the pharmaceutical industry because they can be used for precise and individualized …

Messenger RNA-based therapeutics and vaccines: what's beyond COVID-19?

D Li, C Liu, Y Li, R Tenchov, JM Sasso… - ACS Pharmacology & …, 2023 - ACS Publications
With the rapid success in the development of mRNA vaccines against COVID-19 and with a
number of mRNA-based drugs ahead in the pipelines, mRNA has catapulted to the forefront …

[HTML][HTML] mRNA as a transformative technology for vaccine development to control infectious diseases

G Maruggi, C Zhang, J Li, JB Ulmer, D Yu - Molecular Therapy, 2019 - cell.com
In the last two decades, there has been growing interest in mRNA-based technology for the
development of prophylactic vaccines against infectious diseases. Technological …

[HTML][HTML] mRNA-based vaccines and therapeutics for COVID-19 and future pandemics

VP Chavda, S Soni, LK Vora, S Soni, A Khadela… - Vaccines, 2022 - mdpi.com
An unheard mobilization of resources to find SARS-CoV-2 vaccines and therapies has been
sparked by the COVID-19 pandemic. Two years ago, COVID-19's launch propelled mRNA …

[HTML][HTML] Recent Advancement in mRNA Vaccine Development and Applications

N Al Fayez, MS Nassar, AA Alshehri, MK Alnefaie… - Pharmaceutics, 2023 - mdpi.com
Messenger RNA (mRNA) vaccine development for preventive and therapeutic applications
has evolved rapidly over the last decade. The mRVNA vaccine has proven therapeutic …

mRNA–a game changer in regenerative medicine, cell-based therapy and reprogramming strategies

O Chabanovska, AM Galow, R David… - Advanced Drug Delivery …, 2021 - Elsevier
After thirty years of intensive research shaping and optimizing the technology, the approval
of the first mRNA-based formulation by the EMA and FDA in order to stop the COVID-19 …

[HTML][HTML] mRNA vaccines in disease prevention and treatment

G Zhang, T Tang, Y Chen, X Huang… - Signal Transduction and …, 2023 - nature.com
Abstract mRNA vaccines have emerged as highly effective strategies in the prophylaxis and
treatment of diseases, thanks largely although not totally to their extraordinary performance …

[HTML][HTML] mRNA-based vaccines and therapeutics: an in-depth survey of current and upcoming clinical applications

YS Wang, M Kumari, GH Chen, MH Hong… - Journal of Biomedical …, 2023 - Springer
Abstract mRNA-based drugs have tremendous potential as clinical treatments, however, a
major challenge in realizing this drug class will promise to develop methods for safely …