This paper outlines the major components and function of the technologically integrated oncosimulator developed primarily within the Advancing Clinico Genomic Trials on Cancer …
K Marias, V Sakkalis, A Roniotis, C Farmaki… - World Congress on …, 2010 - Springer
The ContraCancrum project aims at developing a composite multilevel platform for simulating malignant tumor development and tumor and normal tissue response to …
This paper presents a brief outline of the notion and the system of oncosimulator in conjunction with a high level description of the basics of its core multiscale model simulating …
The development of computational models for simulating tumor growth and response to treatment has gained significant momentum during the last few decades. At the dawn of the …
Rapid advancements in high-throughput omics technologies and experimental protocols have led to the generation of vast amounts of scale-specific biomolecular data on cancer …
The" Oncosimulator" is at the same time a concept of multilevel integrative cancer and (treatment affected) normal tissue biology, an algorithmic construct and a software tool which …
S Jafari Nivlouei, M Soltani, E Shirani… - Cell …, 2022 - Wiley Online Library
Objectives Computational modeling of biological systems is a powerful tool to clarify diverse processes contributing to cancer. The aim is to clarify the complex biochemical and …
Application of computer simulation for predicting cancer progression/remission/recurrence is still underestimated by clinicians. This is mainly due to the lack of tumor modeling …
The multiscale complexity of cancer as a disease necessitates a corresponding multiscale modelling approach to produce truly predictive mathematical models capable of improving …