Systemic sclerosis

Y Allanore, R Simms, O Distler… - Nature reviews Disease …, 2015 - nature.com
Systemic sclerosis is a complex autoimmune disease characterized by a chronic and
frequently progressive course and by extensive patient-to-patient variability. Like other …

Systemic sclerosis: current views of its pathogenesis

CT Derk, SA Jimenez - Autoimmunity reviews, 2003 - Elsevier
Systemic sclerosis (SSc) is an autoimmune disorder of unknown etiology characterized by
severe and often progressive cutaneous and visceral fibrosis, pronounced alterations in the …

Systemic sclerosis

ER Volkmann, K Andréasson, V Smith - The Lancet, 2023 - thelancet.com
Systemic sclerosis, also known as scleroderma, is a rare and complex autoimmune
connective-tissue disease. Once considered an untreatable and unpredictable condition …

Pathophysiology of systemic sclerosis: current understanding and new insights

M Cutolo, S Soldano, V Smith - Expert review of clinical …, 2019 - Taylor & Francis
ABSTRACT Introduction: Systemic sclerosis (SSc) is a complex autoimmune connective
tissue disease characterized by chronic and progressive tissue and organ fibrosis with …

[PDF][PDF] Systemic sclerosis–multidisciplinary disease: clinical features and treatment

P Sobolewski, M Maślińska, M Wieczorek… - Reumatologia …, 2019 - termedia.pl
Systemic sclerosis is a chronic autoimmune disease of still not fully understood
pathogenesis. Fibrosis, vascular wall damage, and disturbances of innate and acquired …

Systemic sclerosis: an update

J Varga - Bulletin of the NYU hospital for joint diseases, 2008 - go.gale.com
Systemic sclerosis (SSc) is a complex and heterogeneous chronic illness characterized by
substantial patient to patient variability in clinical manifestations, internal organ involvement …

[HTML][HTML] Systemic sclerosis/scleroderma: a treatable multisystem disease

M Hinchcliff, J Varga - American family physician, 2008 - aafp.org
Systemic sclerosis (systemic scleroderma) is a chronic connective tissue disease of
unknown etiology that causes widespread microvascular damage and excessive deposition …

A comprehensive framework for navigating patient care in systemic sclerosis: a global response to the need for improving the practice of diagnostic and preventive …

LA Saketkoo, T Frech, C Varjú, R Domsic… - Best Practice & …, 2021 - Elsevier
Systemic sclerosis (SSc), the most lethal of rheumatologic conditions, is the cause of death
in> 50% of SSc cases, led by pulmonary fibrosis followed by pulmonary hypertension and …

[HTML][HTML] Update on biomarkers in systemic sclerosis: tools for diagnosis and treatment

AJ Affandi, TRDJ Radstake, W Marut - Seminars in immunopathology, 2015 - Springer
Systemic sclerosis (SSc) is a complex autoimmune disease in which immune activation,
vasculopathy, and extensive fibrosis of the skin and internal organs are among the principal …

Systemic sclerosis in adults. Part I: Clinical features and pathogenesis

R Jerjen, M Nikpour, T Krieg, CP Denton… - Journal of the American …, 2022 - Elsevier
Systemic sclerosis (SSc), also referred to as systemic scleroderma or scleroderma, is a rare,
complex immune-mediated connective tissue disease characterized by progressive skin …