Reward expectation extinction restructures and degrades CA1 spatial maps through loss of a dopaminergic reward proximity signal

S Krishnan, C Heer, C Cherian, MEJ Sheffield - Nature communications, 2022 - nature.com
Hippocampal place cells support reward-related spatial memories by forming a cognitive
map that over-represents reward locations. The strength of these memories is modulated by …

Different encoding of reward location in dorsal and intermediate hippocampus

P Jarzebowski, YA Hay, BF Grewe, O Paulsen - Current Biology, 2022 - cell.com
Hippocampal place cells fire at specific locations in the environment. They form a cognitive
map that encodes spatial relations in the environment, including reward locations. 1 As part …

A role for the locus coeruleus in hippocampal CA1 place cell reorganization during spatial reward learning

AM Kaufman, T Geiller, A Losonczy - Neuron, 2020 - cell.com
During spatial learning, hippocampal (HPC) place maps reorganize to represent new goal
locations, but little is known about the circuit mechanisms facilitating these changes. Here …

Reactivation predicts the consolidation of unbiased long-term cognitive maps

AD Grosmark, FT Sparks, MJ Davis, A Losonczy - Nature Neuroscience, 2021 - nature.com
Spatial memories that can last a lifetime are thought to be encoded during 'online'periods of
exploration and subsequently consolidated into stable cognitive maps through their …

A dedicated population for reward coding in the hippocampus

JL Gauthier, DW Tank - Neuron, 2018 - cell.com
The hippocampus plays a critical role in goal-directed navigation. Across different
environments, however, hippocampal maps are randomized, making it unclear how goal …

Place field assembly distribution encodes preferred locations

O Mamad, L Stumpp, HM McNamara… - PLoS …, 2017 - journals.plos.org
The hippocampus is the main locus of episodic memory formation and the neurons there
encode the spatial map of the environment. Hippocampal place cells represent location, but …

Reward cues in space: commonalities and differences in neural coding by hippocampal and ventral striatal ensembles

CS Lansink, JC Jackson, JV Lankelma… - Journal of …, 2012 - Soc Neuroscience
Forming place-reward associations critically depends on the integrity of the hippocampal–
ventral striatal system. The ventral striatum (VS) receives a strong hippocampal input …

Hippocampus leads ventral striatum in replay of place-reward information

CS Lansink, PM Goltstein, JV Lankelma… - PLoS …, 2009 - journals.plos.org
Associating spatial locations with rewards is fundamental to survival in natural environments
and requires the integrity of the hippocampus and ventral striatum. In joint multineuron …

A hippocampus-accumbens tripartite neuronal motif guides appetitive memory in space

S Trouche, V Koren, NM Doig, TJ Ellender, M El-Gaby… - Cell, 2019 - cell.com
Retrieving and acting on memories of food-predicting environments are fundamental
processes for animal survival. Hippocampal pyramidal cells (PYRs) of the mammalian brain …

Enriched encoding: reward motivation organizes cortical networks for hippocampal detection of unexpected events

VP Murty, RA Adcock - Cerebral Cortex, 2014 - academic.oup.com
Learning how to obtain rewards requires learning about their contexts and likely causes.
How do long-term memory mechanisms balance the need to represent potential …