The plasma metabolome of long COVID patients two years after infection

Y López-Hernández, J Monárrez-Espino, DAG López… - Scientific reports, 2023 - nature.com
One of the major challenges currently faced by global health systems is the prolonged
COVID-19 syndrome (also known as “long COVID”) which has emerged as a consequence …

Metabolomics markers of COVID-19 are dependent on collection wave

HM Lewis, Y Liu, CF Frampas, K Longman, M Spick… - Metabolites, 2022 - mdpi.com
The effect of COVID-19 infection on the human metabolome has been widely reported, but to
date all such studies have focused on a single wave of infection. COVID-19 has generated …

The serum metabolome of COVID-19 patients is distinctive and predictive

D Shi, R Yan, L Lv, H Jiang, Y Lu, J Sheng, J Xie, W Wu… - Metabolism, 2021 - Elsevier
Background Metabolism is critical for sustaining life, immunity and infection, but its role in
COVID-19 is not fully understood. Methods Seventy-nine COVID-19 patients, 78 healthy …

Longitudinal metabolomics of human plasma reveals prognostic markers of COVID-19 disease severity

M Sindelar, E Stancliffe, M Schwaiger-Haber… - Cell Reports …, 2021 - cell.com
There is an urgent need to identify which COVID-19 patients will develop life-threatening
illness so that medical resources can be optimally allocated and rapid treatment can be …

Understanding the pathophysiological changes via untargeted metabolomics in COVID‐19 patients

HO Doğan, O Şenol, S Bolat, ŞN Yıldız… - Journal of medical …, 2021 - Wiley Online Library
Abstract Coronavirus disease 2019 (COVID‐19) is an infectious respiratory disease caused
by a new strain of the coronavirus. There is limited data on the pathogenesis and the cellular …

Metabolite profile of COVID-19 revealed by UPLC-MS/MS-based widely targeted metabolomics

J Liu, ZB Li, QQ Lu, Y Yu, SQ Zhang, PF Ke… - Frontiers in …, 2022 - frontiersin.org
The metabolic characteristics of COVID-19 disease are still largely unknown. Here, 44
patients with COVID-19 (31 mild COVID-19 patients and 13 severe COVID-19 patients), 42 …

Metabolic signatures associated with severity in hospitalized COVID-19 patients

J Marín-Corral, J Rodríguez-Morató… - International journal of …, 2021 - mdpi.com
The clinical evolution of COVID-19 pneumonia is poorly understood. Identifying the
metabolic pathways that are altered early with viral infection and their association with …

Metabolic profiling at COVID-19 onset shows disease severity and sex-specific dysregulation

FC Ceballos, A Virseda-Berdices, S Resino… - Frontiers in …, 2022 - frontiersin.org
Background metabolic changes through SARS-CoV-2 infection has been reported but not
fully comprehended. This metabolic dysregulation affects multiple organs during COVID-19 …

Plasma metabolomic profiling of patients recovered from coronavirus disease 2019 (COVID-19) with pulmonary sequelae 3 months after discharge

J Xu, M Zhou, P Luo, Z Yin, S Wang… - Clinical Infectious …, 2021 - academic.oup.com
Background Elucidation of the molecular mechanisms involved in the pathogenesis of
coronavirus disease 2019 (COVID-19) may help to discover therapeutic targets. Methods To …

The serum metabolome of moderate and severe COVID-19 patients reflects possible liver alterations involving carbon and nitrogen metabolism

M Caterino, M Costanzo, R Fedele, A Cevenini… - International journal of …, 2021 - mdpi.com
COVID-19 is a global threat that has spread since the end of 2019, causing severe clinical
sequelae and deaths, in the context of a world pandemic. The infection of the highly …