Identification and validation of key long non-coding RNAs in resveratrol protect against IL-1β-treated chondrocytes via integrated bioinformatic analysis

H Yi, W Zhang, SY Cui, JB Fan, XH Zhu… - Journal of Orthopaedic …, 2021 - Springer
Abstract Background Long non-coding RNAs (lncRNAs) participate in regulation of gene
transcription, but little is known about the correlation among resveratrol and lncRNAs. This …

LINC02288 promotes chondrocyte apoptosis and inflammation through miR‐374a‐3p targeting RTN3

Q Fu, J Zhu, B Wang, J Wu, H Li, Y Han… - The Journal of Gene …, 2021 - Wiley Online Library
Background Dysregulation of long non‐coding RNAs (lncRNAs) is related to the occurrence
of osteoarthritis (OA). In the present study, we explored the role of LINC02288 and its …

Long non-coding RNA DANCR regulates proliferation and apoptosis of chondrocytes in osteoarthritis via miR-216a-5p-JAK2-STAT3 axis

L Zhang, P Zhang, X Sun, L Zhou, J Zhao - Bioscience reports, 2018 - portlandpress.com
Osteoarthritis (OA) is one of the most common chronic joint disease. Long non-coding RNAs
(lncRNAs) have been confirmed to play important roles in a variety of diseases including OA …

LINC00707 knockdown inhibits IL-1β-induced apoptosis and extracellular matrix degradation of osteoarthritis chondrocytes by the miR-330-5p/FSHR axis

M Qian, Y Shi, W Lu - Immunopharmacology and …, 2022 - Taylor & Francis
Background Osteoarthritis (OA) is a severe disabling condition that causes major health
problems. The roles of long non-coding RNAs (lncRNAs) in regulating OA progression have …

LINC00473 exacerbates osteoarthritis development by promoting chondrocyte apoptosis and proinflammatory cytokine production through the miR‑424‑5p/LY6E axis

G Fan, J Liu, Y Zhang, X Guan - Experimental and …, 2021 - spandidos-publications.com
Osteoarthritis (OA) is a common degenerative joint disease that has been identified as one
of the major health burdens in aging individuals. Long non‑coding RNAs (lncRNAs) …

[HTML][HTML] Systematic analysis of differential expression profile in rheumatoid arthritis chondrocytes using next-generation sequencing and bioinformatics approaches

YJ Chen, WA Chang, LY Wu, YL Hsu… - … Journal of Medical …, 2018 - ncbi.nlm.nih.gov
Cartilage destruction in rheumatoid arthritis (RA) occurs primarily in the pannus-cartilage
interface. The close contact of the synovium-cartilage interface implicates crosstalk between …

LncRNA CASC19 accelerates chondrocytes apoptosis and proinflammatory cytokine production to exacerbate osteoarthritis development through regulating the miR …

C Zhou, T He, L Chen - Journal of Orthopaedic Surgery and Research, 2021 - Springer
Background Osteoarthritis (OA) is one kind of degenerative joint disease that happens in
articular cartilage and other joint tissues. Long non-coding RNAs (lncRNAs) have been …

[HTML][HTML] Expression profile of long noncoding RNAs in cartilage from knee osteoarthritis patients

M Fu, G Huang, Z Zhang, J Liu, Z Huang, B Yu… - Osteoarthritis and …, 2015 - Elsevier
Summary Objectives Long noncoding RNAs (lncRNAs) have emerged as a novel class of
regulatory molecules involved in various biological processes, but their role in osteoarthritis …

LncRNA MEG3 inhibits the degradation of the extracellular matrix of chondrocytes in osteoarthritis via targeting miR-93/TGFBR2 axis

K Chen, H Zhu, MQ Zheng, QR Dong - Cartilage, 2021 - journals.sagepub.com
Background As a degenerative joint disease, osteoarthritis (OA) is characterized by articular
cartilage degradation. Long noncoding RNAs (lncRNAs) act critical roles in the regulation of …

LINC01534 promotes the aberrant metabolic dysfunction and inflammation in IL-1β-simulated osteoarthritic chondrocytes by targeting miR-140-5p

W Wei, S He, Z Wang, J Dong, D Xiang, Y Li… - Cartilage, 2021 - journals.sagepub.com
Objective Long non-coding RNA 01534 (LINC01534) is highly expressed in the tissues of
patients with osteoarthritis (OA). This study investigated the mechanism of LINC01534 on …