Early time-restricted feeding improves 24-hour glucose levels and affects markers of the circadian clock, aging, and autophagy in humans

H Jamshed, RA Beyl, DL Della Manna, ES Yang… - Nutrients, 2019 - mdpi.com
Time-restricted feeding (TRF) is a form of intermittent fasting that involves having a longer
daily fasting period. Preliminary studies report that TRF improves cardiometabolic health in …

Time-restricted eating for the prevention and management of metabolic diseases

ENC Manoogian, LS Chow, PR Taub… - Endocrine …, 2022 - academic.oup.com
Time-restricted feeding (TRF, animal-based studies) and time-restricted eating (TRE,
humans) are an emerging behavioral intervention approach based on the understanding of …

[HTML][HTML] Diurnal transcriptome landscape of a multi-tissue response to time-restricted feeding in mammals

S Deota, T Lin, A Chaix, A Williams, H Le, H Calligaro… - Cell metabolism, 2023 - cell.com
Time-restricted feeding (TRF) is an emerging behavioral nutrition intervention that involves a
daily cycle of feeding and fasting. In both animals and humans, TRF has pleiotropic health …

Fasting, circadian rhythms, and time-restricted feeding in healthy lifespan

VD Longo, S Panda - Cell metabolism, 2016 - cell.com
Most animals alternate periods of feeding with periods of fasting often coinciding with sleep.
Upon> 24 hr of fasting, humans, rodents, and other mammals enter alternative metabolic …

[HTML][HTML] Time-restricted feeding is a preventative and therapeutic intervention against diverse nutritional challenges

A Chaix, A Zarrinpar, P Miu, S Panda - Cell metabolism, 2014 - cell.com
Because current therapeutics for obesity are limited and only offer modest improvements,
novel interventions are needed. Preventing obesity with time-restricted feeding (TRF; 8–9 hr …

Time‐restricted feeding for prevention and treatment of cardiometabolic disorders

GC Melkani, S Panda - The Journal of physiology, 2017 - Wiley Online Library
The soaring prevalence of obesity and diabetes is associated with an increase in
comorbidities, including elevated risk for cardiovascular diseases (CVDs). CVDs continue to …

Time-restricted eating: benefits, mechanisms, and challenges in translation

P Regmi, LK Heilbronn - Iscience, 2020 - cell.com
Eating out of phase with daily circadian rhythms induces metabolic desynchrony in
peripheral metabolic organs and may increase chronic disease risk. Time-restricted eating …

Early or delayed time-restricted feeding prevents metabolic impact of obesity in mice

P Regmi, R Chaudhary, AJ Page… - Journal of …, 2021 - joe.bioscientifica.com
Time-restricted feeding (TRF) initiated early during the dark phase prevents the metabolic
consequences of high fat diet in rodent models. However, the metabolic consequences of …

Time-restricted feeding improves insulin resistance and hepatic steatosis in a mouse model of postmenopausal obesity

H Chung, W Chou, DD Sears, RE Patterson… - Metabolism, 2016 - Elsevier
Background Menopause is associated with significant hormonal changes that result in
increased total body fat and abdominal fat, amplifying the risk for metabolic syndrome and …

[HTML][HTML] Time-restricted feeding without reducing caloric intake prevents metabolic diseases in mice fed a high-fat diet

M Hatori, C Vollmers, A Zarrinpar, L DiTacchio… - Cell metabolism, 2012 - cell.com
While diet-induced obesity has been exclusively attributed to increased caloric intake from
fat, animals fed a high-fat diet (HFD) ad libitum (ad lib) eat frequently throughout day and …