The fetal inflammatory response syndrome (FIRS) is a condition characterized by systemic
inflammation and an elevation of fetal plasma interleukin-6. This syndrome has been …

The fetus can deploy a local or systemic inflammatory response when exposed to
microorganisms or, alternatively, to non-infection-related stimuli (eg, danger signals or …

Objective The aim of this study was to show and discuss an association between fetal
inflammatory response syndrome (FIRS) and an adverse neonatal outcome defined as …

OBJECTIVE: The objective of this study was to determine the frequency and clinical
significance of a systemic inflammatory response as defined by an elevated plasma …

Problem The fetal inflammatory response syndrome (FIRS) is considered the counterpart of
the systemic inflammatory response syndrome (SIRS), but similarities in their regulatory …

Emerging concepts of sepsis suggest that the host response to an infectious stimulus results
in some cases of uncontrolled release of inflammatory cytokines leading to signs of sepsis …

Fetal development and growth occur in a sterile amniotic cavity while first exposure to
microorganisms happens at birth. However, at least 25% of all preterm births, the leading …

Inflammation has been implicated in the mechanisms responsible for preterm and term
parturition, as well as fetal injury. Out of all of the suspected causes of preterm labour and …

Human parturition at term and preterm is an inflammatory process synchronously executed
by both fetomaternal tissues to transition them from a quiescent state t an active state of …

Successful pregnancy requires carefully-coordinated communications between the mother
and fetus. Immune cells and cytokine signaling pathways participate as mediators of these …