Immunotherapies for hepatocellular carcinoma

JM Llovet, F Castet, M Heikenwalder… - Nature reviews Clinical …, 2022 - nature.com
Liver cancer, more specifically hepatocellular carcinoma (HCC), is the second leading
cause of cancer-related death and its incidence is increasing globally. Around 50% of …

Systemic therapy of liver cancer

T Demir, SS Lee, AO Kaseb - Advances in Cancer Research, 2021 - Elsevier
Hepatocellular carcinoma (HCC) is a lethal malignancy with poor prognosis. More than 80%
of patients are diagnosed at an advanced stage, and most patients with HCC also have liver …

Molecular therapies and precision medicine for hepatocellular carcinoma

JM Llovet, R Montal, D Sia, RS Finn - Nature reviews Clinical oncology, 2018 - nature.com
The global burden of hepatocellular carcinoma (HCC) is increasing and might soon surpass
an annual incidence of 1 million cases. Genomic studies have established the landscape of …

Advances in immunotherapy for hepatocellular carcinoma

B Sangro, P Sarobe, S Hervás-Stubbs… - Nature reviews …, 2021 - nature.com
Hepatocellular carcinoma (HCC) is a prevalent disease with a progression that is modulated
by the immune system. Systemic therapy is used in the advanced stage and until 2017 …

Immunotherapies for hepatocellular carcinoma

JKH Liu, AF Irvine, RL Jones, A Samson - Cancer Medicine, 2022 - Wiley Online Library
Cases of hepatocellular carcinoma (HCC) are rapidly rising. This is particularly the case in
the Western world, as a result of increasing rates of chronic liver disease, secondary to …

Immunotherapy for advanced hepatocellular carcinoma: a focus on special subgroups

M Pinter, B Scheiner, M Peck-Radosavljevic - Gut, 2021 - gut.bmj.com
Following the success of immune checkpoint blockers (ICBs) in different cancer types, a
large number of studies are currently investigating ICBs in patients with hepatocellular …

[HTML][HTML] Immunotherapy for advanced hepatocellular carcinoma, where are we?

L Zhang, J Ding, HY Li, ZH Wang, J Wu - Biochimica et Biophysica Acta …, 2020 - Elsevier
A couple of molecular-targeting medications, such as Lenvatinib, are available for the
treatment of hepatocellular carcinoma (HCC) in addition to Sorafenib in an advanced stage …

Hepatocellular carcinoma immunotherapy

RC Sperandio, RC Pestana… - Annual review of …, 2022 - annualreviews.org
Hepatocellular carcinoma (HCC) is the most common primary liver malignancy and the third
leading cause of cancer-related death worldwide. Single-agent anti-PD-1 immune …

Immunological landscape and immunotherapy of hepatocellular carcinoma

J Prieto, I Melero, B Sangro - Nature reviews Gastroenterology & …, 2015 - nature.com
Advanced hepatocellular carcinoma (HCC) is a serious therapeutic challenge and targeted
therapies only provide a modest benefit in terms of overall survival. Novel approaches are …

Biomarkers for immunotherapy of hepatocellular carcinoma

TF Greten, A Villanueva, F Korangy, B Ruf… - Nature Reviews …, 2023 - nature.com
Immune-checkpoint inhibitors (ICIs) are now widely used for the treatment of patients with
advanced-stage hepatocellular carcinoma (HCC). Two different ICI-containing regimens …